Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection
Recruiting · NCT05985785 · Interventional (participants receive a specific treatment) · Lead sponsor: Rush University Medical Center
View the official record on ClinicalTrials.gov →Interventions studied
Autologous bone marrow aspirate concentrate (BMAC)Corticosteroid injectionsCrossover Autologous bone marrow aspirate concentrate (BMAC)
What this trial is about
Prospective single-masked (study participant will be masked), randomized controlled trial to examine the influence of BMAC on patient-reported outcomes (PROs) in patients with primary knee osteoarthritis.
Who can take part
Age range
18 Years to 70 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Patients between the ages of 18-70
- Long standing knee pain from osteoarthritis (KL grade 2-3) despite conventional treatments such as activity modification, weight loss, physical therapy, analgesics, nonsteroidal anti-inflammatory drugs, or injection therapy for at least 6 weeks
- 7-day average pain score of at least 4 on VAS scale
Exclusion criteria
- Systemic diseases (Diabetes, malignancies, infections, etc.)
- Post-traumatic arthritis
- Patient had intra-articular injection on affected knee in last three months
Where it is running
1 location listed across 1 US state.
- Rush University Medical Center - Chicago, Illinois, United States