Fetal Cell Receptors Repertoire
Recruiting · NCT06031714 · Interventional (participants receive a specific treatment) · Lead sponsor: Assistance Publique - Hôpitaux de Paris
View the official record on ClinicalTrials.gov →Interventions studied
Blood samplingClinical examinationInterviewsSaliva sampling
What this trial is about
The purpose of this study is to describe the transcriptomic profile of foetal cells in post-partum and more specifically to determine which chemokine receptors are overexpressed in foetal cells in post-partum women with wounds To do so, the investigators will isolate foetal cells from the peripheral blood of healthy controls post partum women as well as from post partum women with skin ulcers and then perform RNA sequencing.
Who can take part
Age range
No age limits stated
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Common criteria :
- Adult women,
- Post-partum: having been pregnant for any length of time,
- Having signed a free and informed consent form,
- Primiparous or multiparous,
- Affiliated to a health insurance
- Patients :
- \- Patients with a venous, diabetic or sickle cell ulcer, or mixed ulcer
- Control group patients :
- Volunteers,
- Age-matched,
- Without skin ulcers.
- There are no specific criteria for children.
Exclusion criteria
- Minors (for patients)
- Under court protection, curatorship, guardianship (for patients)
- Immunocompromised patients for any reason whatsoever
- Refusal of consent
- Refusal of blood and/or saliva samples for themselves or a member of their family
Where it is running
1 location listed.
- Dermatology unit - Cochin Hospital - APHP - Paris, Île-de-France Region, France