Epileptogenic Network Visualisation With Advanced MRI
Recruiting · NCT06059157 · Interventional (participants receive a specific treatment) · Lead sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this clinical trial is to improve non-invasive identification of epileptogenic networks in drug-resistant epileptic patient. The investigators aim to compare epileptogenic network identification with stereo-EEG (used as glod standard) with the identification of the same network using advanced MRI (rs-fMRI, microstructural analysis of white matter, ...). The main goals are to: 1. Compare the accuracy of network identification. 2. Analyse the effect of the MRI sequences on candidates selection and target identification. Participants will already have been selected for stereoEEG and will undergo a supplementary MRI (about 1h) with the additional MRI sequences. Follow-up MRI are scheduled for patient undergoing a second, therapeutic epileptic surgery.
Who can take part
Inclusion criteria
- Patient suffering from drug-resistant epilepsy
- Patient already selected for SEEG implantation as part of their epileptic networks
Exclusion criteria
- Patient excluded from SEEG (pregnant women, children too young for the procedure, patient unable to undergo the procedure)
- Contra-indication for MRI
Where it is running
1 location listed.
- Cliniques Universitaires St-Luc - Brussels, Belgium