Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)
Recruiting · NCT06071377 · Observational (researchers observe without assigning treatment) · Lead sponsor: National Alliance for Sickle Cell Centers
View the official record on ClinicalTrials.gov →Interventions studied
Biologic Specimen Collection
What this trial is about
The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Are willing to voluntarily participate and sign the study consent
- Know/suspect they have SCT and are willing to get tested to confirm/learn about their SCT status
- Adults ages 18 and older
Exclusion criteria
- Unwilling to sign consent
- Known end-stage renal disease or dialysis
- Known SCD (including sickle cell-beta thalassemia)
- People who do not have SCT
Where it is running
10 locations listed across 8 US states.
- University of Alabama - Birmingham, Alabama, United States
- Loma Linda University Health Care - Loma Linda, California, United States
- Nemours Children's Hospital - Wilmington, Delaware, United States
- Indiana University - Indianapolis, Indiana, United States
- Functional Fluidics - Detroit, Michigan, United States
- University of North Carolina - Chapel Hill, North Carolina, United States
- Duke University - Durham, North Carolina, United States
- East Carolina University - Greenville, North Carolina, United States
- Nationwide Children's Hospital - Columbus, Ohio, United States
- UT Health Houston - Houston, Texas, United States