Wrist Denervation Vs Exercise in Wrist Osteoarthritis
Recruiting · NCT06098586 · Interventional (participants receive a specific treatment) · Lead sponsor: Karolinska Institutet
View the official record on ClinicalTrials.gov →Interventions studied
Partial wrist denervationSelf-managed exercise therapy program
What this trial is about
A randomized controlled trial comparing partial wrist denervation to a self-managed exercise therapy program in 140 patients with wrist osteoarthritis.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age ≥ 18 years.
- Chronic wrist pain (≥6 months) due to Scapholunate advanced collapse (SLAC) / Scaphoid non-union advanced collapse (SNAC) grade 1-3 osteoarthritis.
- Radiological signs of osteoarthritis on posteroanterior and lateral radiograph.
Exclusion criteria
- Previous PIN or AIN neurectomy.
- Rheumatoid arthritis or other chronic inflammatory arthritis.
- Symptomatic osteoarthritis in the distal radio-ulnar (DRU), Scapho-trapezio-trapezoid (STT) or thumb carpometacarpal (CMC) joints.
- Ongoing infection.
- Inability to co-operate with the follow-up protocol.
- Systemic or intra-articular glucocorticoids or intraarticular PRP or Hyaluronic acid injections in the affected joint within 3 months prior to enrollment.
Where it is running
2 locations listed.
- Department of hand surgery, Malmo university hospital - Malmö, Sweden
- Department of hand handsurgery, Södersjukhuset - Stockholm, Sweden