Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data
Recruiting · NCT06380192 · Observational (researchers observe without assigning treatment) · Lead sponsor: Imagine Institute
View the official record on ClinicalTrials.gov →What this trial is about
Developmental and Epileptic Encephalopathy (DEE) are a heterogeneous group of neurodevelopmental disorders linked to both epilepsy and its underlying etiology, independently of epileptiform activity. The creation of a database with retrospective follow-up of a large number of patients on a national scale will enable better knowledge of specific biomarkers, and thus a better classification and understanding of the natural evolution of DEE according to their etiology. This will enable better, more personalized therapeutic management of patients, depending on etiology and the presence or absence of these biomarkers. The investigators will also be able to draw up management recommendations, which are currently non-existent.
Who can take part
Inclusion criteria
- Diagnosis of Developmental and Epileptic Encephalopathy
- Registered with or benefiting from a social security scheme.
Exclusion criteria
- Opposition of the patient or his/her parents to the re-use of data in the context of this study
- Person subject to a safeguard of justice measure
Where it is running
23 locations listed.
- CHU Amiens - Amiens, France
- CH Angers - Angers, France
- Chu Besancon - Besançon, France
- CHU Bordeaux - Bordeaux, France
- CHRU Brest - Brest, France
- CHU Clermont-Ferrand - Clermont-Ferrand, France
- CHU Grenoble - Grenoble, France
- CHU Lille - Lille, France
- CHU Limoges - Limoges, France
- CHU Lyon HCL - Lyon, France
- Assistance Publique Hopitaux de Marseille - Marseille, France
- CHU de Nancy - Nancy, France
- Hopitaux Pediatriques de Nice CHU Lenval - Nice, France
- Necker-Enfants Malades Hospital - Paris, France
- CHU Pitié Salpétrière - Paris, France
- CHU Robert Debré - Paris, France
- Hôpital Armand Trousseau - Paris, France
- Chu Reims - Reims, France
- CHU Rennes - Rennes, France
- CHU Strasbourg - Strasbourg, France
- CHU Toulouse - Toulouse, France
- CHRU Tours - Tours, France
- Hôpital André Mignot (CH Versailles) - Versailles, France