Antidepressant Adherence for Depressed Adults in Primary Care
Recruiting · NCT06496646 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Pennsylvania
View the official record on ClinicalTrials.gov →Interventions studied
Arm 1 interventionArm 2 Intervention
What this trial is about
The goal of this study is to test ways to help people improve their health and manage their medication for depression. This study will measure both medication adherence and depression outcomes.
Who can take part
Age range
21 Years to 64 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Penn Medicine primary care outpatients
- Clinical diagnosis of major depressive disorder
- A score of 10+ on the Patient Health Questionnaire 9 (PHQ-9)
- Age 21 to 64 years at the time of study entry
- Prescribed an antidepressant by their primary care clinician
- Express interest in taking antidepressant medication
- Own a cell phone
- Capable of using the electronic pill bottle
- English-speaking
Exclusion criteria
- Treated with antidepressants in the past 90 days
- Pregnant or breastfeeding
- An active substance use disorder other than nicotine
- A lifetime history of treatment for bipolar disorder or schizophrenia
- Hospital admission or emergency department visit for suicidal symptoms in the past year
- Lack capacity to provide informed consent
- Using antidepressant more than 10 days at baseline assessment
Where it is running
1 location listed across 1 US state.
- University of Pennsylvania Health System - Philadelphia, Pennsylvania, United States