Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis
Recruiting · NCT06514703 · Interventional (participants receive a specific treatment) · Lead sponsor: Zagazig University
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this study is to evaluate the comparative effectiveness of CT-guided and fluoroscopic-guided genicular nerve ablation in reducing knee pain and improving function in adults diagnosed with knee osteoarthritis refractory to conservative treatment. The main questions it aims to answer are: * Does CT-guided genicular nerve ablation provide superior pain relief compared to fluoroscopic-guided genicular nerve ablation? * Is there a significant difference in functional improvement between the two techniques? Researchers will compare the outcomes between the CT-guided and fluoroscopic-guided groups to determine which method achieves better pain relief, functional enhancement, safety profile, and patient satisfaction. Participants will: * Undergo either CT-guided or fluoroscopic-guided genicular nerve ablation. * Attend scheduled follow-up visits to assess pain levels, knee function, and any adverse events. * Complete standardized questionnaires to provide feedback on pain relief, functional improvement, and overall satisfaction with the procedure.
Who can take part
Inclusion criteria
- Adults aged 45 to 80 years.
- Diagnosed with knee osteoarthritis.
- Knee osteoarthritis refractory to conservative treatment.
- Able to provide informed consent.
- Agree to follow the study procedures and attend follow-up visits.
Exclusion criteria
- Prior knee surgery within the last six months.
- Contraindications to genicular nerve ablation (e.g., certain types of infections, bleeding disorders).
- Severe comorbid conditions that may interfere with the study outcomes (e.g., rheumatoid arthritis, other severe autoimmune diseases).
- Current participation in another clinical trial that could interfere with the outcomes of this study.
- Allergy or sensitivity to the materials used in the ablation procedures.
Where it is running
1 location listed.
- Zagazig University, Faculty of Medicine - Zagazig, Sharqia Province, Egypt