High-resolution Multi-parametric Magnetic Resonance Imaging for Focal Epilepsy
Recruiting · NCT06550726 · Interventional (participants receive a specific treatment) · Lead sponsor: Chinese University of Hong Kong
View the official record on ClinicalTrials.gov →Interventions studied
Magnetic Resonance Imaging
What this trial is about
Patients with focal epilepsy often have diagnostic difficulties as their culprit for seizures are difficult to be picked up using conventional imaging. The current study is to investigate the utility of advanced MRI sequences on detection of subtle lesions accountable for focal epilepsy.
Who can take part
Age range
No age limits stated
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Consecutive patients with drug-resistant focal epilepsy fulfilling the following criteria -
- \. Diagnosis of focal epilepsy with a probable site identified, as defined by concordant results from any TWO of the following:
- Clinical seminology compatible with focal epilepsy.
- Electroencephalography pointing towards a specific site for focal epilepsy.
- Positive ictal brain scintigraphy with SPECT-CT correlation. AND 2. Previous MRI (at least one study with protocol tailored for epilepsy) which did not reveal accountable focal lesion.
- AND 3. Able to consent for MRI examination (if patient under age of 18, consent for MRI will be obtained from guardian). Patients will be provided information leaflets to read on, and written consent before taking part in this study and MRI examination.
Exclusion criteria
- Patients who are contraindicated to magnetic resonance imaging (such as due to underlying MRI incompatible metallic implants)
- Patients who cannot cooperate for MRI scanning.
- Patients show are unable to provide informed consent.
Where it is running
1 location listed.
- Gerald Choa MRI Center - Hong Kong, Hong Kong