Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Pain, Anxiety and Depression in Patients With Resectable Head and Neck Squamous Cell Carcinoma
Recruiting · NCT06575322 · Observational (researchers observe without assigning treatment)
View the official record on ClinicalTrials.gov →Interventions studied
Anti-PD-1 DrugsCarboplatin（ neoadjuvant）Paclitaxel （neoadjuvant）Surgical resection
What this trial is about
The goal of this observational study is to learn about the Effects of neoadjuvant therapy with carboplatin, paclitaxel combined with anti-PD-1 drugs on pain, anxiety and depression in patients with operable head and neck squamous cell carcinoma: a prospective cohort study
Who can take part
Age range
18 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- \- 1: Clinical diagnosis of head and neck squamous cell carcinoma (stage I-IVA), without prior treatment, and planning to undergo either surgical treatment alone or surgical treatment combined with chemotherapy and immunotherapy.
- : Ability to speak Chinese and possess basic reading and writing skills.
Exclusion criteria
- 1: Presence of mental illnesses such as dementia or delirium.
- : Active use of narcotic drugs, including consuming alcohol more than 4 times per day or more than 4 times per week.
- : Patients who alter their treatment plan during the course of treatment.
- : Current or prior use of antidepressants.
Where it is running
1 location listed.
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University - Guanzhou, Guangdong, China