Advancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease
Recruiting · NCT06770010 · Interventional (participants receive a specific treatment) · Lead sponsor: Children's National Research Institute
View the official record on ClinicalTrials.gov →Interventions studied
Cogmed+
What this trial is about
This is a single site nonrandomized pilot clinical trial of the feasibility, acceptability, and efficacy of a combination treatment involving digital Cogmed working memory skills training, social support components, and memory strategy training to improve adherence to Cogmed in youth with sickle cell disease ages 7-16 years.
Who can take part
Age range
7 Years to 16 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Diagnosis of sickle cell disease (any genotype).
- Between ages 7-16 years old.
- Patients will only enter the treatment phase if they score \>1 SD below the normative mean on at least one standardized working memory assessment (i.e., Digit Span or Spatial Span subtests) or demonstrate a relative weakness in working memory (\>1 SD below the estimated IQ).
Exclusion criteria
- Motor, visual, or auditory impairment that prevents computer use.
- Diagnosis of a mental health condition that precludes, or takes treatment precedence over, participation in the cognitive training.
- History of photosensitive seizures.
- Insufficient English fluency.
- Recent initiation or dose adjustment of a stimulant medication to treat attention problems (\< 30 days).
Where it is running
1 location listed across 1 US state.
- Children's National Hospital - Washington D.C., District of Columbia, United States