Endometriosis and Migraine
Recruiting · NCT06785129 · Observational (researchers observe without assigning treatment) · Lead sponsor: Washington University School of Medicine
View the official record on ClinicalTrials.gov →Interventions studied
Conditioned pain modulation (CPM) responseHormonal assessmentPain ratingsPressure stimuliThermal stimuli
What this trial is about
This study aims to determine differences in experimental pain and sex hormone levels between patients with migraine, patients with endometriosis, patients with migraine and endometriosis, and healthy controls. Participants will complete surveys, experimental pain paradigms and collection of samples for hormone analyses.
Who can take part
Age range
12 Years to 45 Years
Sex
Female
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Patients with diagnosed endometriosis, migraine, or both endometriosis and migraine
- Healthy control subjects with no history of chronic pain
- Age 12-45
- Assigned female sex at birth
Exclusion criteria
- Pregnancy or breastfeeding
- Presence of prolactinoma
- Presence of psychiatric, neurological, endocrinological and/or developmental conditions and taking medications for these conditions
- Current use of dopamine agonist or SSRI medications
- For patients aged 12-17 not having a parent/legal guardian willing to sign the consent and answer surveys about their child's health
Where it is running
2 locations listed across 1 US state.
- Washington University School of Medicine - St Louis, Missouri, United States
- Washington University School of Medicine - St Louis, Missouri, United States