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A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
NCT05552157 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 37 locations
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A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
NCT06647498 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 37 locations
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A Study to Find and Confirm Blood-based Markers (Called Proteins) That May Show Early Heart Changes in Women With Preeclampsia, Even Before Symptoms Appear, and the Use of Heart Ultrasound (Echocardiography) to Look at Patterns of How the Heart Changes During Pregnancy in Women With Preeclampsia
NCT07463898 ·
Phase: Not specified ·
Ages: 13 Years to 50 Years ·
Sex: Female · 1 location
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Adapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics
NCT06063564 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female) · 1 location
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Adolescent Chatbot
NCT07094503 ·
Phase: Phase 2 ·
Ages: 13 Years to 19 Years ·
Sex: All (male and female) · 2 locations
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Advancing Biopsychosocial Care Training Initiative
NCT07049861 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 5 Years and older ·
Sex: All (male and female) · 1 location
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Amygdala Memory Enhancement
NCT05065450 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female) · 1 location
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Beta Amyloid PET Imaging for Alzheimer Disease With [18F]-Fluselenamyl
NCT06439992 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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BettER: Biomarker Driven Early Therapeutic Selection in Patients With HR+ HER2- Metastatic or Unresectable Breast Cancer
NCT05977036 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
NCT05277558 ·
Phase: Not specified ·
Ages: 12 Years to 17 Years ·
Sex: All (male and female) · 2 locations
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Brain Imaging and Immune Changes During Remibrutinib Treatment in Multiple Sclerosis.
NCT07758270 ·
Phase: Not specified ·
Ages: 40 Years to 70 Years ·
Sex: All (male and female) · 1 location
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CARE Tool Study Aim 3
NCT07296887 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female) · 6 locations
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CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma
NCT07241117 ·
Phase: Phase 4 ·
Ages: 12 Years and older ·
Sex: All (male and female) · 7 locations
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COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients
NCT05972343 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Cerebral Oxygen Metabolism in Children
NCT04157179 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 3 Years to 50 Years ·
Sex: All (male and female) · 1 location
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Cerebrovascular Reactivity Measurements With High-Density Diffuse Optical Tomography
NCT07776444 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 6 Years to 70 Years ·
Sex: All (male and female) · 1 location
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Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
NCT04354064 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female) · 3 locations
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Cryoablation vs Lumpectomy in T1 Breast Cancers
NCT05505643 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years and older ·
Sex: Female · 1 location
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Depression and Driving
NCT05446805 ·
Phase: Not specified ·
Ages: 65 Years and older ·
Sex: All (male and female) · 2 locations
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Diffusion Basis Spectrum Imaging of the Prostate
NCT04420702 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Male · 1 location
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Disruptions of Brain Networks and Sleep by Electroconvulsive Therapy
NCT05905705 ·
Phase: Not specified ·
Ages: 21 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Dominantly Inherited Alzheimer Network (DIAN)
NCT00869817 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female) · 26 locations
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Effect of Ketone Esters on Liver Fat Content and Metabolic Function
NCT07097506 ·
Phase: Phase 2 ·
Ages: 18 Years to 40 Years ·
Sex: All (male and female) · 1 location
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Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells
NCT00353483 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
NCT02476786 ·
Phase: Phase 2 ·
Ages: 70 Years and older ·
Sex: Female · 1 location
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Endometriosis Pain
NCT06101303 ·
Phase: Not specified ·
Ages: 12 Years to 45 Years ·
Sex: Female · 1 location
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Endometriosis and Migraine
NCT06785129 ·
Phase: Not specified ·
Ages: 12 Years to 45 Years ·
Sex: Female · 2 locations
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Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer
NCT03516708 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 4 locations
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Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung Cancer Screening at Christian Hospital
NCT07146568 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 20 Years and older ·
Sex: All (male and female) · 2 locations
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Evaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics
NCT06397729 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female) · 1 location
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Fresh RX: NHS 2020
NCT04845230 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 14 Years to 55 Years ·
Sex: Female · 1 location
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Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With Obesity
NCT07091500 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years to 75 Years ·
Sex: All (male and female) · 1 location
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HFrEF Polypill in Sri Lanka RCT
NCT07569640 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 11 locations
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Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain
NCT07270406 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 25 Years to 65 Years ·
Sex: All (male and female) · 1 location
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INCLUDE Program: A Perioperative Wellness Program Tailored for Black Surgical Patients
NCT07283783 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female) · 2 locations
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Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System
NCT07109427 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years to 75 Years ·
Sex: Male · 1 location
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Implementation and Effectiveness of the BJC-Pink and Pearl Project on Lung Cancer Screening
NCT06898333 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Implementing a Randomized Control Trial to Test the Expanded Web-based Decision Aid
NCT06910670 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Improving Maternal Cardiovascular Outcomes Through the Implementation of a Hypertensive Disorders of Pregnancy Bundle in Nigeria
NCT06859359 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: No age limits stated ·
Sex: Female · 4 locations
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Interdisciplinary Group Care for the Treatment of Endometriosis-associated Pain
NCT06549985 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 48 Years ·
Sex: Female · 1 location
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Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1
NCT06129838 ·
Phase: Not specified ·
Ages: 50 Years and older ·
Sex: All (male and female) · 1 location
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Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain
NCT06978166 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years and older ·
Sex: All (male and female) · 1 location
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Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy
NCT06689800 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 8 Years and older ·
Sex: All (male and female) · 1 location
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MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma
NCT06648434 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Mechanism of Ketogenic Diet-Induced Hypercholesterolemia
NCT06894004 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 39 Years ·
Sex: All (male and female) · 1 location
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Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors
NCT05629546 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial
NCT05975593 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Migraine in Adolescents
NCT05654012 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 10 Years to 13 Years ·
Sex: All (male and female) · 1 location
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Mindfulness to Enhance Cognitive Health in Latino Older Adults
NCT07040904 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 65 Years and older ·
Sex: All (male and female) · 1 location
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Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease
NCT06976853 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female) · 3 locations
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NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
NCT02994433 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Neuroimaging of Parkinson's
NCT07024875 ·
Phase: Not specified ·
Ages: 40 Years and older ·
Sex: All (male and female) · 1 location
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ONT01 and Gemcitabine/Nab-paclitaxel as Second Line Therapy for Metastatic Pancreatic Ductal Adenocarcinoma
NCT06904378 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma
NCT04318717 ·
Phase: Phase 2 ·
Ages: 16 Years and older ·
Sex: All (male and female) · 1 location
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Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease
NCT06529822 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 3 locations
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Precision Imaging to Evaluate Kaposi Sarcoma
NCT06898203 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female) · 2 locations
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Propranolol for the Treatment of Kaposi Sarcoma in Adults
NCT06445166 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma
NCT06141031 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 2 locations
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Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
NCT03128996 ·
Phase: Phase 1, Phase 2 ·
Ages: 1 Day to 21 Years ·
Sex: All (male and female) · 4 locations
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Role of KATP Channel Loss in Type 2 Diabetes
NCT06830096 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 2 locations
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Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate Brachytherapy
NCT03424850 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: Male · 1 location
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Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)
NCT07155200 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Small Extracellular Vesicles and Insulin Action
NCT05933707 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 25 Years to 55 Years ·
Sex: All (male and female) · 1 location
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Smoldering Inflammation in MS
NCT06591429 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma
NCT07126158 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Study to Understand Novel Biomarkers in Researching Dementia
NCT06547099 ·
Phase: Not specified ·
Ages: 60 Years and older ·
Sex: All (male and female) · 1 location
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Suubi4PrEP: Improving PrEP Access and Adherence Among Adolescent Girls and Young Women in Uganda
NCT07002866 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 15 Years to 24 Years ·
Sex: Female · 2 locations
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The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF)
NCT05562167 ·
Phase: Phase 2 ·
Ages: 19 Years to 79 Years ·
Sex: All (male and female) · 1 location
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This Study Involves a Positron Emission Tomography (PET) Scan Using a New Investigational Radioactive Tracer, [18F]-FZTA, to Detect Inflammation in the Brain. The Tracer Will be Tested in Healthy Younger Adults and Individuals With Multiple Sclerosis.
NCT07115017 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Treatment Monitoring of Patients Receiving CDK 4/6 Inhibitors for Hormone Receptor (HR) Positive, HER2 Negative Metastatic Breast Cancer (MBC) With or Without the Addition of DiviTum® Serum Thymidine Kinase 1 (TK1) Activity Testing
NCT04968964 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Ultra-Hypofractionated vs. Hypofractionated Radiation for Node-Positive Breast Cancer
NCT06559540 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: Female · 1 location
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Ultrasound and Photoacoustic Imaging for Enhanced Differential Diagnosis of Rectal Cancer
NCT04339374 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 19 Years and older ·
Sex: All (male and female) · 1 location
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Uterine Preservation Via Lifestyle Transformation
NCT05903131 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: Female · 3 locations
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Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism
NCT05088798 ·
Phase: Phase 2 ·
Ages: No age limits stated ·
Sex: All (male and female) · 1 location
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WashU DIEP Flap Video and Patient Understanding Improvement
NCT06864754 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female · 1 location
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Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)
NCT06340646 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis
NCT06374459 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 3 locations
Washington University School of Medicine is the lead sponsor of 77 recruiting
trials.