Platelet Rich Plasma Versus Corticosteroids in Hip Osteoarthritis Pain
Recruiting · NCT06793982 · Interventional (participants receive a specific treatment) · Lead sponsor: LifeBridge Health
View the official record on ClinicalTrials.gov →Interventions studied
Corticosteroid InjectionPlatelet Rich Plasma Joint Injection
What this trial is about
Prospective, single-center that may go on to being multicenter, randomized trial comparing platelet rich plasma (PRP) versus corticosteroid injection for the treatment of symptoms of Hip osteoarthritis. The purpose of the study is to determine which therapy provides a greater reduction in patient reported outcome measures of pain and function.
Who can take part
Age range
21 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Provision of signed and dated informed consent form
- Stated willingness to comply with all study procedures and availability for the duration of the study
- Male or female, aged 21-80 years
- Radiographic diagnosis of Kellgren-Lawrence (KL) grade of II or III Hip osteoarthritis
- Indicated for a Hip injection to treat Hip OA symptoms
Exclusion criteria
- Any injections into the target Hip within three months
- Current overlying skin infection
- Current or previous diagnosis of "chronic pain"
- Opioid tolerant at time of screening (for a week or longer, at least 60 mg of morphine daily, or at least 30 mg of oral oxycodone daily, or at least 8 mg of oral hydromorphone daily or an equianalgesic dose of another opioid.)
- Allergy to any potential ingredients or medications utilized in any of the two groups
- Treatment with another investigational drug or other intervention for pain
- Diagnosis of Diabetes Mellitus
- If female, pregnant or planning to be pregnant within the following 3 months or study duration
- Any condition(s) or diagnosis, both physical or psychological, or physical exam finding in the opinion of the investigator that would precludes participation
Where it is running
1 location listed across 1 US state.
- Sinai Hospital of Baltimore - Baltimore, Maryland, United States