Orexin Gene in Anorexia Nervosa
Recruiting · NCT06800898 · Observational (researchers observe without assigning treatment) · Lead sponsor: Istituto Auxologico Italiano
View the official record on ClinicalTrials.gov →Interventions studied
Blood samples and Questionnaires
What this trial is about
The objectives of this study will be to determine the methylation of the promoter of the Orexin A (OX-A) and B (OX-B) genes in young women (\> 18 years) with Anorexia Nervosa (AN), compared with a control group; and to evaluate the relationship of promoter methylation of the genes for OX-A and OX-B with the severity of the eating disorder, psychiatric comorbidities (in particular, depression), and sleep quality.
Who can take part
Age range
18 Years and older
Sex
Female
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Female sex
- Age 18 years and older
- Anorexia Nervosa
- Hospitalized at the Division of Eating and Nutrition Disorders, Istituto Auxologico Italiano, IRCCS, Piancavallo, Italy
Exclusion criteria
- Absence of signed informed consent
- Control group:
- Inclusion Criteria:
- Female sex
- Age 18 years and older
- Body Mass Index between 18.5 and 24.9 kg/m2
- Exclusion Criteria:
- Absence of signed informed consent
- Presence of any physical and mental pathology
Where it is running
1 location listed.
- Istituto Auxologico Italiano IRCCS, Site Piancavallo - Oggebbio, Verbania, Italy