A Pilot Study of Synbiotics in Adults With Depressive Symptoms
Recruiting · NCT06905223 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
MQU10
What this trial is about
This study aims to explore the efficacy and safety of a synbiotic formula (MQU10) in improving mood and well-being in adults with mild to moderate depressive symptoms.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Individuals aged 18 or above
- Patient Health Questionnaire-9 (PHQ-9) score between 5 to 14
- Literate and can complete the self-report questionnaires
- Able to understand the consent and sign the informed consent form
Exclusion criteria
- Current diagnosis of substance abuse or dependence;
- A current or past history of bipolar disorder, manic or hypomanic episodes, schizophrenia, personality disorder, posttraumatic stress disorder (PTSD), intellectual disability, neurodegenerative disorders (e. g, Parkinson's disease) or organic mental disorder
- Requiring immediate psychiatric care (e. g, imminently suicidal subjects) or have attempted suicide in the past 3 months
- Use of antipsychotics, antidepressants or sedatives, unless on a stable dose in the last 4 weeks
- History of severe organ failure, renal failure on dialysis, HIV infection
- Active malignancy within 5 years
- History of major surgery on the gastrointestinal tract, except cholecystectomy and appendectomy in the past 5 years
- Night shift work
- History of antibiotic use within 4 weeks
- History of allergy to probiotics or lactose leading to a severe allergic reaction
- Known pregnancy or lactating
Where it is running
2 locations listed.
- GenieBiome Limited - Hong Kong, Hong Kong
- Healthymind Centre - Hong Kong, Hong Kong