HLA Antibodies in Systemic Lupus Erythematosus
Recruiting · NCT06921239 · Observational (researchers observe without assigning treatment) · Lead sponsor: Centre Hospitalier Universitaire, Amiens
View the official record on ClinicalTrials.gov →What this trial is about
Patients suffering from autoimmune diseases show false-positive results when anti-HLA antibodies are identified. This false positivity makes it difficult to obtain an organ transplant based on immunological compatibility (absence of anti-HLA antibodies directed against graft antigens). The objectives of this project are to study the prevalence of these false positivities in a population of lupus patients, and to evaluate biological tests that can negate these false positivities.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Patients Adults
- Followed in the internal medicine department of Amiens University Hospital - With systemic lupus erythematosus
- Without HLA immunization risk factors (no history of pregnancy, transfusions or transplants)
- With sera stored in the biobank
Exclusion criteria
- minor Patients
- Opposing the re-use of their personal data for research purposes
Where it is running
1 location listed.
- CHRU Amiens - Amiens, France