Clinical trials recruiting for Lupus
332
Recruiting trials
39
US states with sites
67
Countries
12%
Accept healthy volunteers
Phase breakdown
Drugs and treatments being studied
Where trials are recruiting (top US states)
| State | Recruiting trials |
|---|---|
| Texas | 37 |
| California | 36 |
| New York | 35 |
| Florida | 28 |
| North Carolina | 25 |
| Illinois | 22 |
| Pennsylvania | 20 |
| Georgia | 19 |
| Maryland | 18 |
| Ohio | 18 |
| Michigan | 15 |
| Tennessee | 15 |
Top cities
New York, New York 24Houston, Texas 17Philadelphia, Pennsylvania 15Atlanta, Georgia 14Chicago, Illinois 14Miami, Florida 13Tampa, Florida 12Boston, Massachusetts 10Charlotte, North Carolina 10Los Angeles, California 10
Self-screener
Recruiting trials
- " TREX1 Gene Mutations and Their Role in Systemic Lupus Erythematosus
- 2-HOBA in Systemic Lupus Erythematosus
- A Clinical Study Exploring the Safety, Efficacy and Cell Metabolic Dynamics of Universal CD19 / 20 Car-t Cell Injection in Moderate to Severe Refractory Systemic Lupus Erythematosus
- A Clinical Study of CD19 CAR-T in Active Systemic Lupus Erythematosus
- A Clinical Study of CD19 Universal CAR-γδT Cells in Active Systemic Lupus Erythematosus
- A Clinical Study of Dual-Target, Universal CAR-T Cell Therapy for Refractory Systemic Lupus Erythematosus
- A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)
- A Clinical Study of TI-0032-III Injection in Patients With Relapsed and Refractory Autoimmune Diseases
- A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases
- A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases
- A Clinical Study of YTS109 Cell in R/R Systemic Lupus Erythematosus
- A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases
- A Clinical Trial on the Efficacy and Safety of TQH3906 in the Treatment of Systemic Lupus Erythematosus
- A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
- A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus
- A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
- A Phase 1 Study of HB2198 in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE)
- A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)
- A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants
- A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
- A Phase 1b/2a Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
- A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
- A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G
- A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis
- A Phase 3 Clinical Study of MIL62 in Systemic Lupus Erythematosus
- A Phase II Clinical Study on the Efficacy and Safety of SHR-2173 Injection in the Treatment of Patients With Active Lupus Nephritis
- A Phase IIa Study of ICG318 CAR-T in Refractory Systemic Lupus Erythematosus With or Without Lupus Nephritis
- A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment
- A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
- A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)
- A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
- A Study of APG-2575 in Patients With Mild-to-moderate Systemic Lupus Erythematosus.
- A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy
- A Study of CC312 for Relapsed/Refractory Autoimmune Diseases
- A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
- A Study of D-2570 in Patients With Active Systemic Lupus Erythematosus (SLE)
- A Study of E6742 in Participants With Systemic Lupus Erythematosus
- A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
- A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
- A Study of GNC-038 Tetra-specific Antibody Injection in Patients With Systemic Lupus Erythematosus
- A Study of GR1803 in Systemic Lupus Erythematosus
- A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants
- A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD)
- A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
- A Study of IMC-002 for the Treatment of Active Systemic Lupus Erythematosus
- A Study of Intravenous CPTX2309 in Healthy Participants and Participants With Moderate to Severe Rheumatoid Arthritis (RA) or Systemic Lupus Erythematosus (SLE)
- A Study of LCAR-AIO in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus
- A Study of LUCAR-G79D in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE) and Idiopathic Inflammatory Myopathies (r/r IIM)
- A Study of LY4298445 in Healthy Participants and Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)
- A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
- A Study of OL-108 in Relapsed/Refractory Autoimmune Diseases
- A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus Nephritis
- A Study of Quinacrine in Participants With Cutaneous Lupus Erythematosus
- A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)
- A Study of SCTB35 in Patients with Systemic Lupus Erythematosus
- A Study of SHR-2173 in Participants With Systemic Lupus Erythematosus
- A Study of Telitacicept in Lupus Nephritis
- A Study on the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of SHR-7012 in Healthy Adults
- A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)
- A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE), Sjogren's Disease (SjD) and Rheumatoid Arthritis (RA)
- A Study to Assess the Safety and PK/PD of LBL-047 in Healthy Adults and Patients With Systemic Lupus Erythematosus
- A Study to Continue the Administration of Deucravacitinib in Participants With Systemic Lupus Erythematosus (SLE) or Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE) Who Have Completed Study IM011074 or Study IM011132
- A Study to Evaluate Mosunetuzumab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis
- A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
- A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
- A Study to Evaluate the Efficacy, Safety, and Tolerability of Human Sialidase Fusion Protein (HLX79) in Combination With Rituximab Injection Versus Placebo in Patients With Active Glomerulonephritis
- A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic Diseases
- A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus
- A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
- A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
- A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE
- A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
- AGR+PNI as Predictors of Systemic Lupus Erythematosus Disease Activity
- Achievement of LLDAS5 in Patients With Systemic Lupus Erythematosus Treated With Anifrolumab.
- Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease
- Allogeneic UCB-derived CAR-T for SLE
- Alnuctamab for Refractory SLE (LATTE Study)
- An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease
- An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants
- An Exploratory Clinical Study of Anti-CD19 CAR NK Cells in the Treatment of Systemic Lupus Erythematosus
- An Exploratory Clinical Study of SCAR02 Targeting BCMA and CD19 for the Treatment of Refractory Autoimmune Diseases
- An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases
- An Exploratory Study of CD19/CD22/BCMA CAR-T Cells (BZE2204) in Subjects With Relapsed or Refractory Autoimmune Diseases
- Anifrolumab Malignancy and Serious Infections Study
- Anifrolumab Pregnancy Study
- Anti CD19/BCMA CAR Gene Therapy for Autoimmune Diseases
- Anti-C1s, Anti-HMGB1 and Anti-C1q Autoantibodies in Systemic Lupus Erythematosus (DYSALARM-322)
- Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune Diseases
- Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus
- Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases
- Anti-CD19/BCMA CAR-NK Cells in Patients With B Cell Mediated Autoimmune Disease
- Argentinian Prospective Registry of Patients With Lupus
- Assessing Residual Inflammation and Macrophage Presence in Lupus Nephritis After 3 Months of Intensified Treatment With Prednisolone, Mycofenolate Mofetil and Voclosporin as Compared to Mycofenolate Mofetil and Prednisolone
- Assessment of Hematologic Indices in Juvenile Lupus Erythematosus Patients:Correlation With Disease Activity and Chronic Organ Damage in These Patients
- Assessment of Physician Consideration of EPRO's, from Patients with Gout, Rheumatoid Arthritis, Sjogren's Syndrome or Systemic Lupus, on the Frequency of Therapeutic Adjustments
- Autologous CD19 Car T-Cell Therapy For Severe Refractory Systemic Lupus Erythematosus (SLE)
- Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmune Diseases
- Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases
- BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus
- BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases
Related conditions
Trials recruiting for Lupus often also study these conditions. Each links to its own recruiting-trial list.
Systemic lupus erythematosus 119Rheumatoid arthritis 314Lupus Nephritis 49Systemic Sclerosis (SSc) 28Systemic Sclerosis 27Autoimmune Diseases 29Lupus Nephritis (LN) 20Lupus Erythematosus, Systemic 20Psoriasis 233Multiple sclerosis 445
Common questions
Are these trials free to join?
Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.
How do I know if I am eligible for Lupus trials?
Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.
Is this list complete?
No. For the full list, search ClinicalTrials.gov.