Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis
Recruiting · NCT06937528 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Jordan
View the official record on ClinicalTrials.gov →Interventions studied
Extracellular vesicles
What this trial is about
Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosis
Who can take part
Age range
42 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 1
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Severe KOA stage III or IV by Laurance \& Kellgren staging as judged by Posterioranterior (PA) Xray of the knee joint.
- Willing to participate by signing the informed consent
Exclusion criteria
- Sublaxation beyond 20 degrees of the bones of the knee joint
- Oral anticoagulants or heparin therapy
- Heart failure or arrhythmia
- Body Mass Index \> 35
- Uncontrolled Diabetes Mellitus.
- Evidence of Infectious Diseases.
- Active infection
- Malignancy
- Pregnancy
- Anemia less than 11g/dl or thrombocytopenia less than 100,000 or leucopenia less than 3000.
- Unreliable patients
- Non-resident in Jordan
Where it is running
1 location listed.
- Cell Therapy Center - Amman, Jordan