Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients
Recruiting · NCT07001189 · Observational (researchers observe without assigning treatment) · Lead sponsor: Centre Hospitalier Universitaire de la Guadeloupe
View the official record on ClinicalTrials.gov →What this trial is about
Sickle cell disease is a chronic disease characterized by multiple vaso-occlusive complications. The basic treatment for patients with a vaso-occlusive crisis (VOC) is based on adequate hydration, oxygen therapy and pain control. Loco Regional Anesthesia (LRA) is one of the major treatments in resuscitation anesthesia for both anesthesia and analgesia. LRA allows effective and almost immediate pain control by blocking nerve afferents in a given area. LRA could decrease the inflammatory response during crises and accelerate resolution of the crisis.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- patients adult \>18 years
- patients with vaso-occlusive crisis
Exclusion criteria
- Pregnant or breastfeeding women
- Blood transfusion within the last 3 months
- Lack of affiliation with the French social security system
- Protected individuals
Where it is running
1 location listed.
- Chu de La Guadeloupe - Pointe-à-Pitre, Guadeloupe