AGR+PNI as Predictors of Systemic Lupus Erythematosus Disease Activity
Recruiting · NCT07043153 · Observational (researchers observe without assigning treatment) · Lead sponsor: Sohag University
View the official record on ClinicalTrials.gov →Interventions studied
Albumin to globulin ratio and prognostic nutritional index model
What this trial is about
This study aims to evaluate the clinical utility of combining the albumin to globulin ratio (AGR) and the prognostic nutritional index (PNI) as a predictive model for assessing disease activity in patients with systemic lupus erythematosus (SLE). By correlating these nutritional and inflammatory markers with clinical manifestations and laboratory parameters, we hope to establish a simple, non-invasive, and cost-effective tool to aid in monitoring disease activity in Systemic lupus erythematosus patients.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- · Age ≥ 18 years.
- Both sexes.
- Patients diagnosed with SLE who fulfilling the Systemic Lupus International Collaborating Clinics (SLICC) classification criteria and matched controls.
Exclusion criteria
- Co-existing chronic inflammatory or autoimmune diseases.
- Age \<18 years
- Malignancy.
- Pregnancy or lactation.
- Chronic liver or renal insufficiency.
- Malignant hematologic diseases.
- Active hepatitis.
- Acute infection within the previous four weeks
Where it is running
1 location listed.
- Sohag University hospitals - Sohag, Egypt