NYU Epilepsy Self-Management Study
Recruiting · NCT07087821 · Interventional (participants receive a specific treatment) · Lead sponsor: NYU Langone Health
View the official record on ClinicalTrials.gov →Interventions studied
Enhanced Usual CarePACESUPLIFT
What this trial is about
The investigators will conduct two-arm randomized controlled trials (RCTs) comparing effects of UPLIFT vs. enhanced usual care and PACES vs. enhanced usual care, respectively, on quality of life, depressive symptoms and seizures over 12 months in NYU patients with epilepsy.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Adults (≥18 years)
- English-speaking (UPLIFT and PACES) or Spanish-speaking (UPLIFT only).
- Diagnosed with epilepsy for at least one year
- Able to understand the informed consent and provide consent
- Elevated depressive symptoms - Patient Health Questionnaire-9 (PHQ-9) score ≥10; applies to UPLIFT only
Exclusion criteria
- Severe depressive symptoms (score of ≥20 on PHQ-9)
- Active suicidal ideation (score of ≥1 on PHQ-9 item #9 or otherwise reported during screening)
- Active psychotic disorder (psychiatric diagnosis and/or antipsychotic medications in the electronic health records (EHR)
- Significant cognitive impairment (indicated in the EHR or evident during screening)
Where it is running
2 locations listed across 1 US state.
- NYU Langone Health - NYU Langone Hospital-Brooklyn - Brooklyn, New York, United States
- NYU Langone Health - NYU Comprehensive Epilepsy Center - New York, New York, United States