Tissue Engineered Cartilage to Repairing Articular Cartilage Defects

Inclusion criteria

• The patients' age ranges from 18 to 65 years old, and gender is not restricted;
• The imaging results show that the epiphyseal growth is mature;
• The defects or localized injuries of joint cartilage caused by trauma or other reasons;
• The injured area is the distal weight-bearing surface of the femoral condyle of the knee joint, with no more than 4 lesions, and there is no injury to the cruciate ligaments;
• The patients voluntarily sign and provide a written informed consent form and are willing to closely cooperate with the doctor's strict postoperative rehabilitation program.

Exclusion criteria

• The patient is extremely overweight, with a body mass index greater than 35;
• The lower limb alignment is valgus by more than 10° and varus by more than 5°;
• Multiple ligament injuries;
• There are numerous bad habits such as heavy smoking, drug abuse, and excessive alcohol consumption;
• Has undergone open knee joint surgery within the past six months;
• Has severe joint stiffness or fibrosis;
• Has an allergic constitution or a history of allergic reactions to collagen;
• Has mental abnormalities;
• Cannot or is unwilling to undergo rehabilitation training;
• Has primary cardiovascular diseases, lung diseases, endocrine and metabolic disorders, or other serious diseases that affect their daily life, such as tumors or AIDS;
• Pregnant or lactating women, or those planning to conceive during the trial period;
• Other acute or chronic diseases, for which the researchers consider surgery to be inappropriate.