Evaluation of the Cryocheck HexLA Integrated TCA for the Detection of Lupus Anticoagulant
Recruiting · NCT07313475 · Observational (researchers observe without assigning treatment) · Lead sponsor: University Hospital, Strasbourg, France
View the official record on ClinicalTrials.gov →What this trial is about
Lupus anticoagulant (LA) testing is performed using two screening tests: activated partial thromboplastin time (APTT) and diluted Russell's viper venom time. If one of the screening tests is positive, a confirmation test based on the same principle is performed. The HUS Hematology Laboratory uses an integrated APTT for LA testing, consisting of a screening reagent: Cephen LS, and a confirmation reagent: Cephen (Hyphen Biomed). The aim of this study is to determine whether another integrated activated partial thromboplastin time (APTT) test, Cryocheck HexLA, offers better performance than Cephen LS/Cephen, both in terms of sensitivity to lupus anticoagulant (LA) and susceptibility to interference from anticoagulant treatments.
Who can take part
Inclusion criteria
- Patient of legal age (≥ 18 years)
- Sample sent to the HUS Hematology Laboratory and analyzed for LA detection as part of routine care.
Exclusion criteria
- \- Insufficient sample volume
Where it is running
1 location listed.
- Laboratoire d'Hématologie - CHU de Strasbourg - France - Strasbourg, France