geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry
Recruiting · NCT07380906 · Observational (researchers observe without assigning treatment) · Lead sponsor: Joint & Vascular Institute
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of genicular artery embolization (GAE) for knee osteoarthritis in adults aged 18 years or older with symptomatic KOA that has not responded to medical therapy. The main questions it aims to answer are: 1. Does GAE lead to sustained improvement in pain (WOMAC, VAS) and quality-of-life scores over 12-36 months? 2. What patient or procedural factors are associated with better outcomes after GAE? Participants will: * Undergo GAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines. There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.
Who can take part
Inclusion criteria
- Adults (≥18 years) with symptomatic KOA refractory to medical therapy, referred for GAE.
Exclusion criteria
- Pregnancy, coagulopathy, severe comorbidities, or inability to consent.
Where it is running
1 location listed across 1 US state.
- Joint and Vascular Institute - Libertyville, Illinois, United States