A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
Recruiting · NCT07477704 · Interventional (participants receive a specific treatment) · Lead sponsor: Regeneron Pharmaceuticals
View the official record on ClinicalTrials.gov →Interventions studied
Alirocumab
What this trial is about
This study is researching an experimental drug called alirocumab, referred to as "study drug". In the United States, alirocumab is approved for the treatment of hypercholesterolemia (high blood cholesterol levels). The aim of the study is to see how safe and effective alirocumab is when given weekly to adult participants who have hypercholesterolemia. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug once a week * How much study drug is in the blood at different times
Who can take part
Age range
18 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 2
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- \. Participant has elevated LDL-C level, as defined in the protocol
- Key
Exclusion criteria
- Participant plans to initiate or change dose of lipid-lowering therapy
- Use of any PCSK9 inhibitors
- NOTE: Other Protocol-Defined Inclusion/Exclusion Criteria Apply
Where it is running
34 locations listed across 19 US states.
- Pinnacle Research Group - Anniston, Alabama, United States
- Cullman Clinical Trials - Cullman, Alabama, United States
- Anaheim Clinical Trials - Anaheim, California, United States
- Cenexel CNS - Los Alamitos, California, United States
- Diablo Clinical Research - Flourish Research - Walnut Creek, California, United States
- Tampa Bay Medical Research - Clearwater, Florida, United States
- Southwest General Healthcare Center - Fort Myers, Florida, United States
- Precision Clinical Research - Sunrise, Florida, United States
- K2 Medical Research The Villages - The Villages, Florida, United States
- Center for Advanced Research and Education - Gainesville, Georgia, United States
- Balanced Life Health Care Solutions - Lawrenceville, Georgia, United States
- East-West Medical Research Institute - Honolulu, Hawaii, United States
- L-MARC Research Center - Louisville, Kentucky, United States
- Tandem Clinical Research - Marrero, Louisiana, United States
- Mercury Street Medical Group, PLLC - Butte, Montana, United States
- Velocity Clinical Research - Omaha - Omaha, Nebraska, United States
- Palm Research Center, Mountainview Medical Center - Las Vegas, Nevada, United States
- Velocity Clinical Research - Durham - Durham, North Carolina, United States
- Accellacare of Wilmington - Wilmington, North Carolina, United States
- Ohio Clinical Trials - Columbus, Ohio, United States
- AMR Norman - Norman, Oklahoma, United States
- Lynn Health Science Institute - Oklahoma City, Oklahoma, United States
- Velocity Clinical Research, Medford - Medford, Oregon, United States
- Altoona Center for Clinical Research - Duncansville, Pennsylvania, United States
- Tribe Clinical Research - Greenville, South Carolina, United States
- Coastal Carolina Research Center_North Charleston - North Charleston, South Carolina, United States
- Velocity Clinical Research Dallas - Dallas, Texas, United States
- Valley Institute of Research, Rockwood Medical Clinic - Fort Worth, Texas, United States
- Be Well Clinical Studies - Round Rock - Round Rock, Texas, United States
- Flourish Research - San Antonio Medical Trials - San Antonio, Texas, United States
- Endeavor Clinical Trials - San Antonio, Texas, United States
- Consano Clinical Research, LLC - Shavano Park, Texas, United States
- Charlottesville Medical Research - Charlottesville, Virginia, United States
- Rainier Clinical Research Center - Renton, Washington, United States