A Decentralized Clinical Study Evaluating the Effectiveness of Two Different Doses of MyCondro™ on Physical Mobility and Joint Health

Inclusion criteria

• Individuals age 45 years and older.
• BMI range between 18-35 kg/m².
• Self-reported mobility issues, including mobility impairment and joint discomfort associated with a known diagnosis of Knee Osteoarthritis. This impairment and discomfort must have persisted for at least 6 months prior to randomization and have been actively experienced within the last 3 months.
• Willingness to avoid high Chondroitin Sulfate-containing foods (i.e., animal cartilages, bones, or derivatives such as gelatin) for the duration of the study period.
• Willingness to refrain from supplements containing Chondroitin Sulfate for the duration of the study period.
• Able to read and understand English.
• Able to read, understand, and provide informed consent.
• Able to use a personal smartphone device and download the Chloe by People Science app.
• Able to receive shipments of the product at an address within the United States.
• Able to complete study assessments over the course of up to 16 weeks.

Exclusion criteria

• Any potential participants will be excluded if they meet any of the following criteria:
• Technology Limitation: Do not have a personal smartphone, lack internet access, or are unwilling to download the Chloe app.
• Concomitant Therapies
• Use of a Chondroitin Sulfate supplement in the 3 months prior to randomization.
• Current use of other joint health supplements (e.g., glucosamine, hyaluronic acid, collagen peptides) for at least 4 weeks prior to randomization.
• Use of any intra-articular or intravenous steroid injections in the last 3 months.
• Receiving any investigational therapies or treatments within 30 days prior to randomization.
• ther Illnesses or Conditions
• Self-reported inflammatory arthropathies, such as Rheumatoid Arthritis, Gout, and Infectious Arthritis.
• Significant systemic lung, liver, heart, or kidney disease (excluding hypertension).
• Prior history of knee surgery within 3 months preceding the study period, or planned knee surgery (including arthroscopy) during the study period.
• Currently diagnosed with Alcohol Use Disorder and/or Substance Use Disorder.
• Currently pregnant, planning to become pregnant in the next 20 weeks, or breastfeeding.
• Presence of a knee prosthesis.
• Any significant illness, disease, or condition which, in the opinion of the Principal Investigator, may impact the ability to participate in the study or impact the study outcomes.
• Allergies and Intolerances
• Known hypersensitivity or previous allergic reaction to: Chondroitin sulfate, Maltodextrin, Mannitol, Magnesium Stearate, Silicon dioxide, Microcrystalline cellulose, or Talc.
• Known sensitivity or intolerance to wheat or gluten.
• General Compliance
• Unlikely for any reason to be able to comply with the trial, or considered unsuited for participation in the study by the Principal Investigator.