ETASCAN Project: ETAS Project 2
Recruiting · NCT07550140 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Reading
View the official record on ClinicalTrials.gov →Interventions studied
ETAS®Placebo
What this trial is about
This study aims to investigate the chronic effects of ETAS® on cognitive, affective and neural outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.
Who can take part
Age range
60 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Aging between 60-80 years old
- Having normal vision and hearing
- Having a body mass index between 18.5 and 30
- Having mild to moderate subjective cognitive complaints
Exclusion criteria
- Smoking
- Having food allergies
- Following restrictive and/or unbalanced diets (Appendix 6: Are you vegetarian or vegan? Yes / No; Are you currently on a weight-reducing or other special diet? Yes/No If 'Yes', please give details.)
- Being diagnosed with any psychiatric or neurologic conditions (e.g. schizophrenia, depression, dementia) including eating disorders
- Being diagnosed with any cardiometabolic diseases (including type II diabetes and cardiovascular disease), or hypertension or thrombosis related disorders or suffer from thyroid disease
- Currently taking anticoagulants, antiplatelet medication, antidepressants, proton-pump inhibitors
- Currently consuming prebiotic or probiotic supplements
- Continuous antibiotic use for \> 3 days within 1 month prior to enrolment
- Continuous use of weight-loss drug for \> 1 month before screening
- Having a significant gastrointestinal (GI) condition affecting absorption including (but not limited to) inflammatory bowel disease; total colectomy or bariatric surgery; irritable bowel disease; end stage renal disease; active cancer, or treatment for any cancer, in last 3 years
- History of claustrophobia
- Fitted with a pacemaker or artificial heart valve
- Have active implants, such as cochlear, ocular, or penile implant
- Experience of metal fragments e.g. shrapnel in your eyes or any other part of your body
- Drug infusion pump installed
- Have any surgically implanted metal in any part of your body, other than dental fillings and crowns (e.g. joint replacement or bone re-construction)
- Have had any surgery that might have involved metal implants
- Current or historical experience of epilepsy
- Have stimulators for nerves, brain or bone installed
- Have an intrauterine contraceptive device installed (IUD)
- Wear transdermal patches containing metal
- Wear a filling, crown, dental post (entirely within the tooth) associated with root canal treatment, retainer, bridge or braces
- For scanning, would need to remove coloured contact lenses, nail polish and makeup.
- Hearing aid wearer
- Body piercings that you cannot or will not remove for the scanning session
- Have tattoos or permanent makeup
Where it is running
2 locations listed.
- University of Reading, School of Psychology and Clinical Languages - Reading, Berkshire, United Kingdom
- University of Reading, School of Psychology and Clinical Languages - Reading, Berkshire, United Kingdom