Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection
Recruiting · NCT07804446 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
Anterolateral InjectionAnteromedial Injection
What this trial is about
The primary purpose of this study is to find out if there is a difference in pain experienced in patients with knee arthritis of the inside of their knee if they get a steroid injection on the inside or outside of their knee. Participants will: 1. Be randomly divided into getting their steroid injection on the inside or outside of their knee. 2. Answer a pain survey before their injection as well as over the phone 2 weeks, 6 weeks, and 12 weeks after their injection.
Who can take part
Age range
40 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age ≥ 40
- Clinical diagnosis of knee OA with predominant medial compartment symptoms
- Radiographic moderate-to-severe medial compartment OA (KL grade 3-4 or equivalent)
- Agreed to and preparing to receive a CSI of the knee as part of standard care from surgeon, regardless of past injection of the knee
- Able to provide informed consent
- Able to complete phone, email, or MyChart follow-ups in English
Exclusion criteria
- Predominant lateral compartment OA or patellofemoral-only OA
- Inflammatory arthritis (RA, gout flare, etc.)
- Suspected or confirmed joint infection or overlying cellulitis
- Prior knee arthroplasty on the index knee
- Planned surgery for index knee within 12-week follow-up
- Inability to complete follow-up assessments
- Other clinician-determined contraindication to CSI
Where it is running
5 locations listed across 1 US state.
- Bolingbrook Clinic - Bolingbrook, Illinois, United States
- Hyde Park Clinic - Chicago, Illinois, United States
- La Grange Clinic - La Grange, Illinois, United States
- Orland Park Clinic - Orland Park, Illinois, United States
- Woodridge Clinic - Woodridge, Illinois, United States