-
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
NCT06428409 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
NCT07186842 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
A Phase 1/1b Study of IAM1363 in HER2 Cancers
NCT06253871 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
NCT06695845 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Littleton
-
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
NCT04929223 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora, Lone Tree
-
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
NCT04657068 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
NCT06750094 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora, Denver
-
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
NCT06662786 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
NCT03526835 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Lone Tree
-
A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
NCT06657144 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)
NCT07011576 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
NCT05669430 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
NCT07503808 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers
NCT06663319 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors
NCT07066657 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora, Denver
-
A Study of NX-1607 in Adults With Advanced Malignancies
NCT05107674 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy
NCT06362369 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
NCT07549412 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Lone Tree
-
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
NCT03093116 ·
Phase: Phase 1, Phase 2 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer
NCT07227168 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
NCT05253651 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora, Boulder, Colorado Springs, Denver
-
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
NCT06179160 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
NCT06948448 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Lone Tree
-
A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
NCT06720987 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
NCT07213609 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation
NCT07535112 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.
NCT07235293 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora, Highlands Ranch
-
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
NCT06885034 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies
NCT04678648 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
CT-95 in Advanced Cancers Associated With Mesothelin Expression
NCT06756035 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT05334069 ·
Phase: Not specified ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female)
· Colorado: Aurora, Boulder, Centennial, Colorado Springs
-
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
NCT05174169 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora, Brighton, Colorado Springs, Denver
-
Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
NCT05612347 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 65 Years to 82 Years ·
Sex: All (male and female)
· Colorado: Aurora
-
DESTINY-PANTUMOUR04
NCT07124000 ·
Phase: Not specified ·
Ages: 18 Years to 130 Years ·
Sex: All (male and female)
· Colorado: Boulder
-
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
NCT06239194 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain
NCT06848348 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Wheat Ridge
-
Efficacy and Safety of the CG-100 Intraluminal Bypass Device
NCT04184973 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 70 Years ·
Sex: All (male and female)
· Colorado: Aurora
-
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
NCT07018869 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Colorado Springs, Durango, Lakewood, Longmont
-
Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
NCT05732623 ·
Phase: Not specified ·
Ages: 18 Years to 49 Years ·
Sex: All (male and female)
· Colorado: Denver
-
FOG-001 in Locally Advanced or Metastatic Solid Tumors
NCT05919264 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
Family Communications After Genetic Testing
NCT07143487 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Colorado Springs, Durango, Lakewood, Longmont
-
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
NCT05080673 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years to 70 Years ·
Sex: All (male and female)
· Colorado: Aurora, Boulder, Centennial, Colorado Springs
-
Implementation of a ColoRectal Cancer Screening Tool in US Primary Care Practices - Usual Quality Improvement (10 Clinics) vs Normalization Process Theory-Participatory Learning in Action (10 Clinics)
NCT06682650 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· Colorado: Aurora
-
Improving Care for Rural Patients With Solid Tumors
NCT04916990 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Colorado: Aurora, Colorado Springs, Fort Collins, Grand Junction
-
Integrated Cancer Repository for Cancer Research
NCT02012699 ·
Phase: Not specified ·
Ages: 19 Years to 110 Years ·
Sex: All (male and female)
· Colorado: Greenwood Village
-
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
NCT06026410 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
NCT06073431 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora, Boulder, Centennial, Denver
-
LYL273 for Patients With Relapsed or Refractory mCRC
NCT05319314 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
Lynch Syndrome Integrative Epidemiology and Genetics
NCT06582914 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
NCT06586515 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
Novel Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer
NCT07759921 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Colorado: Aurora
-
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
NCT05059444 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
NCT03715933 ·
Phase: Phase 1 ·
Ages: 12 Years to 85 Years ·
Sex: All (male and female)
· Colorado: Aurora
-
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
NCT05786924 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
NCT07292298 ·
Phase: Phase 2 ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Colorado: Aurora
-
Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
NCT05517811 ·
Phase: Not specified ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Colorado: Aurora, Highlands Ranch
-
SMP-3124LP in Adults With Advanced Solid Tumors
NCT06526819 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
NCT03452774 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Colorado: Aurora, Denver, Littleton
-
Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
NCT07030257 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
NCT06128551 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
NCT03947385 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
NCT06445062 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
NCT05176483 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Littleton
-
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
NCT07283939 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Colorado Springs, Durango, Lakewood, Longmont
-
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
NCT07222800 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora, Boulder, Centennial, Colorado Springs
-
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
NCT04485013 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Denver
-
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
NCT04851119 ·
Phase: Phase 1, Phase 2 ·
Ages: 12 Months to 30 Years ·
Sex: All (male and female)
· Colorado: Aurora
-
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
NCT05863195 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Colorado: Aurora
-
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
NCT04585750 ·
Phase: Phase 1, Phase 2 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· Colorado: Denver