-
A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
NCT07348666 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 13 Years to 24 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
NCT07115329 ·
Phase: Phase 2 ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female)
· Pennsylvania: Allentown, Moosic, Philadelphia
-
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
NCT07592689 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
NCT03887715 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Moosic, Philadelphia
-
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
NCT07172516 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Pennsylvania: Allentown
-
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
NCT06775379 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Pennsylvania: Allentown, Philadelphia
-
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
NCT07412756 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Pennsylvania: Media, Philadelphia
-
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
NCT06793397 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
NCT06524830 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Moosic, Philadelphia
-
A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression
NCT07610473 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Pennsylvania: Allentown, Media
-
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
NCT07300969 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Pennsylvania: Media
-
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
NCT07065240 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Allentown
-
A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT07196501 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Acoustic Stimulation, Sleep, and Cognitive-Emotional Processes in Young Adults With Anxiety and Depression Symptoms
NCT05802004 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 25 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Amygdala Neurofeedback for Depression - Large Scale Clinical Trial
NCT05703256 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Antidepressant Adherence for Depressed Adults in Primary Care
NCT06496646 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years to 64 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Apimostinel + Automated Neurocognitive Training for Depression
NCT06400121 ·
Phase: Phase 2 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Assessing Improvements in Mood and Sleep Trial
NCT06639477 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Brief Smartphone Treatment Study
NCT04846777 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: University Park
-
Bright Light Therapy for OSA
NCT05917119 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project
NCT02434393 ·
Phase: Not specified ·
Ages: 65 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention
NCT05748730 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 18 Years ·
Sex: All (male and female)
· Pennsylvania: Johnstown, Philadelphia, Pittsburgh, Reading
-
Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program
NCT05789446 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 11 Years and older ·
Sex: All (male and female)
· Pennsylvania: Harrisburg, Hershey, Spring Mills, State College
-
Decoding and Modulating Affective Brain States
NCT05437705 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Students
NCT07240792 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 13 Years to 18 Years ·
Sex: All (male and female)
· Pennsylvania: Hershey
-
E-Mindfulness Approaches for Living After Breast Cancer
NCT06748222 ·
Phase: Phase 3 ·
Ages: 18 Years to 50 Years ·
Sex: All (male and female)
· Pennsylvania: Carlisle, Chambersburg, Danville, Dickson City
-
Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device
NCT07389473 ·
Phase: Not specified ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
NCT06830044 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Media
-
Evaluation of the PACE/PACENET BHL Clinical Program
NCT02463266 ·
Phase: Not specified ·
Ages: 65 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Fear of Recurrence and Stopping Immunotherapy
NCT04761328 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Foundational Programs to Combat Clinician Stress
NCT07220421 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 25 Years to 70 Years ·
Sex: All (male and female)
· Pennsylvania: Lancaster, Philadelphia
-
Get ActivE Study for At-risk Youth
NCT06829953 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 18 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia, Pittsburgh
-
Green Light for Post-Operative Wellness
NCT07218289 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Impact of Depression on Thermoregulation
NCT06805851 ·
Phase: Not specified ·
Ages: 18 Years to 40 Years ·
Sex: All (male and female)
· Pennsylvania: University Park
-
Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project)
NCT07020572 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 13 Years to 17 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT06966401 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
NCT07494305 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT06963021 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Neuro-affective Response to Light in Depressed Adolescents and Young Adults
NCT05712772 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 30 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Neurofeedback to Treat Depression - 2
NCT07159061 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Parent Encouragement And Coaching of Happiness in Youth
NCT06725160 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 4 Years to 99 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
NCT06559306 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine
NCT06788249 ·
Phase: Early Phase 1 ·
Ages: 25 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Postpartum Care in the NICU (PeliCaN) Transitions
NCT06521398 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 16 Years and older ·
Sex: Female
· Pennsylvania: Philadelphia
-
Preoperative Opioid Tapering Before Spine Surgery
NCT07221786 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadephia
-
Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care
NCT05869552 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 24 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
NCT07226232 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy
NCT07573150 ·
Phase: Not specified ·
Ages: 3 Years to 17 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
NCT07002034 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
RISE Versus Advocacy-based Enhanced Care as Usual for Patients Experiencing IPV
NCT06906302 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty
NCT05658796 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Pennsylvania: Monroeville, Pittsburgh
-
Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments
NCT06976840 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Removing Surrogates Uncertainty to Reduce Fear and Anxiety After Cardiac Events - Kids
NCT07707037 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 0 Days to 17 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Retrospective Analyses of TrakStar Database
NCT06917339 ·
Phase: Not specified ·
Ages: 5 Years to 120 Years ·
Sex: All (male and female)
· Pennsylvania: Malvern
-
Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments
NCT06997549 ·
Phase: Not specified ·
Ages: 5 Years to 100 Years ·
Sex: All (male and female)
· Pennsylvania: Malvern
-
Risk and Resilience to Suicide Following Late-Life Spousal Bereavement
NCT06191484 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 65 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Sleep Promotion Program Primary Care
NCT06240325 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 18 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Sleep and Circadian Interventions for College Students at High Risk of Suicide
NCT07346014 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 25 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder
NCT07079826 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Study of ALTO-300 in MDD
NCT05922878 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Pennsylvania: Allentown, Media, Moosic
-
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
NCT05850689 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Taking Action for College Students
NCT06700902 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Technology Assisted Collaborative Care Intervention to Improve Patient-centered Outcomes in Dialysis Patients
NCT06978127 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Teen Brain Online II: Understanding How Social Media Affects the Teen Brain
NCT06817993 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 13 Years to 17 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
-
Telehealth Collaborative Care Model (CoCM) in Lung Cancer
NCT07102147 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)
NCT06963463 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 18 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia, Pittsburgh
-
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
NCT06423430 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 70 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Triage Survey for Psychiatry Research Eligibility
NCT05800925 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
-
Video-feedback Intervention to Promote Racial-Ethnic Socialization Competency (VIP-RACE)
NCT07055906 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 10 Years to 14 Years ·
Sex: All (male and female)
· Pennsylvania: Harrisburg
-
Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
NCT06547489 ·
Phase: Phase 2 ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female)
· Pennsylvania: Allentown