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A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression
NCT06597695 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female) · 1 location
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ACT for Individuals With MNCD and Their Care Partners
NCT07239609 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 2 locations
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Accelerated rTMS vs. Sham for Stroke Apathy
NCT07113067 ·
Phase: Phase 1, Phase 2 ·
Ages: 40 Years and older ·
Sex: All (male and female) · 1 location
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Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease
NCT05685368 ·
Phase: Phase 1, Phase 2 ·
Ages: 14 Years to 21 Years ·
Sex: All (male and female) · 1 location
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Adaptation and Validation of the Hypomanic Personality Scale (HPS-6) to Romanian
NCT07399626 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 50 Years ·
Sex: All (male and female) · 1 location
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Adjunctive Allogeneic Mesenchymal Stem Cells for Treatment-resistant Bipolar Depression
NCT03522545 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Affect of Duavive on Mood & Anxiety Symptoms
NCT04478305 ·
Phase: Phase 1 ·
Ages: 45 Years to 60 Years ·
Sex: Female · 2 locations
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Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
NCT05915013 ·
Phase: Phase 1 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female) · 1 location
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Cannabidiol Oil for Treatment-Resistant Major Depression
NCT07696871 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 69 Years ·
Sex: All (male and female) · 1 location
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DBS for Depression
NCT06096207 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Dapagliflozin in Depression
NCT07239011 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female) · 1 location
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ENA-001 for Opioid Induced Respiratory Depression
NCT06967259 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female) · 3 locations
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Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression
NCT06088732 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female) · 1 location
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Effects of Intranasal Oxytocin in Patients With Arginine-vasopressin Deficiency
NCT04789148 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Effects of Low-intensity Transcranial Magnetic Stimulation on Major Depressive Disorder, and on 5-hydroxyindoleacetic Acid and Brain-derived Neurotrophic Factor Levels
NCT06667180 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female) · 1 location
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Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects
NCT07490353 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female) · 1 location
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Enoxolone in Major Depression - Biomarker-outcome Relationship
NCT05570110 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department
NCT06085937 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 2 locations
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Focused Research On Neurofeedback Therapy In Eradicating Depression (FRONTIER)
NCT06557525 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression
NCT06480201 ·
Phase: Phase 1 ·
Ages: 21 Years to 45 Years ·
Sex: All (male and female) · 2 locations
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Ketamine for Combined Depression and Alcohol Use Disorder
NCT06090422 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for Refractory Anorexia Nervosa With Comorbid Obsessive Compulsive Disorder or Major Depressive Disorder
NCT07113665 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 2 locations
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Maternal Mental Health Trial
NCT04685148 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 45 Years ·
Sex: Female · 1 location
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Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
NCT03973268 ·
Phase: Phase 1 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female) · 1 location
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Modulating Exercise Dosage to Improve Concussion Recovery
NCT05434130 ·
Phase: Phase 1, Phase 2 ·
Ages: 13 Years to 18 Years ·
Sex: All (male and female) · 3 locations
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Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains
NCT06795451 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female) · 1 location
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NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
NCT02994433 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Neural Response to Inflammatory Challenge in Major Depressive Disorder
NCT04751331 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
NCT03065335 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Open-Label Psilocybin Study in Transdiagnostic Population
NCT06442423 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 2 locations
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PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)
NCT04582916 ·
Phase: Phase 1 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female) · 1 location
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Pattern Separation in Major Depressive Disorder
NCT07139834 ·
Phase: Phase 1 ·
Ages: 18 Years to 50 Years ·
Sex: All (male and female) · 1 location
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Personalized Ultrasonic Brain Stimulation for Depression (R61)
NCT06902298 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine
NCT07185815 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female) · 6 locations
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Pharmacologic Augmentation of TMS for Depression With D-serine
NCT06876129 ·
Phase: Phase 1 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female) · 1 location
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Psilocybe Cubensis Mushrooms With or Without Fluoxetine for Refractory Depression
NCT06898606 ·
Phase: Phase 1, Phase 2 ·
Ages: 25 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Psilocybin as a Novel Therapy for Residual Anhedonia
NCT07607938 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Psilocybin in Chronic Low Back Pain and Depression
NCT06355414 ·
Phase: Phase 1 ·
Ages: 21 Years to 80 Years ·
Sex: All (male and female) · 1 location
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Psilocybin to Treat Depression in Spinal Cord Injury
NCT07251491 ·
Phase: Phase 1, Phase 2 ·
Ages: 22 Years and older ·
Sex: All (male and female) · 1 location
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RCT of Psilocybin-assisted CBT for Depression
NCT07281352 ·
Phase: Phase 1, Phase 2 ·
Ages: 21 Years to 60 Years ·
Sex: All (male and female) · 1 location
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Roxadustat for Bone and Neuropsychiatric Aspects in Hemodialysis Patients
NCT06917950 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)
NCT05814640 ·
Phase: Phase 1, Phase 2 ·
Ages: 13 Years to 18 Years ·
Sex: All (male and female) · 1 location
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Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans
NCT06671977 ·
Phase: Phase 1 ·
Ages: 21 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Theta-Burst Stimulation to Treat Depression
NCT07033780 ·
Phase: Phase 1 ·
Ages: 18 Years to 50 Years ·
Sex: All (male and female) · 1 location
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[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET
NCT05703685 ·
Phase: Phase 1 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female) · 1 location
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qEEG Brain Signature of Depression & Neuromodulation-induced Recovery
NCT06719427 ·
Phase: Phase 1 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female) · 2 locations