Phase 1 Heart failure trials recruiting now

All Heart failure trials, every phase

Other phases for Heart failure

Phase 1 Heart failure trials

• : Vascular Function in Health and Disease
  NCT02966665 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Clinical Study of HRS-5765 in Healthy Participants
  NCT07551167 · Phase: Phase 1 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• A Clinical Study of HRS-7156 in Healthy Participants
  NCT07601087 · Phase: Phase 1 · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
  NCT07137338 · Phase: Phase 1 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 3 locations
• A Phase I/II Clinical Trial of Intramyocardial Injection of HucMSCs for the Treatment of Chronic Heart Failure
  NCT07265349 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 4 locations
• A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure
  NCT07218627 · Phase: Phase 1 · Ages: 40 Years to 75 Years · Sex: All (male and female) · 1 location
• A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
  NCT07465653 · Phase: Phase 1 · Ages: 18 Years to 100 Years · Sex: All (male and female) · 4 locations
• A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
  NCT07219511 · Phase: Phase 1 · Ages: 50 Years and older · Sex: All (male and female) · 21 locations
• A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy Participants
  NCT07656454 · Phase: Phase 1 · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• A Study of LY3971297 in Participants With Heart Failure
  NCT07547540 · Phase: Phase 1 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 12 locations
• A Study of Metformin to Improve Cardiac Function After LVAD Implantation
  NCT07666698 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 5 locations
• Autologous Induced Pluripotent Stem Cells of Cardiac Lineage for Congenital Heart Disease
  NCT05647213 · Phase: Phase 1 · Ages: 18 Years to 40 Years · Sex: All (male and female) · 1 location
• Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension
  NCT06770023 · Phase: Phase 1 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 2 locations
• Cardiovascular Genistein Therapy for Heart Failure Inflammation
  NCT06501768 · Phase: Phase 1, Phase 2 · Ages: 40 Years to 80 Years · Sex: All (male and female) · 1 location
• Genistein in trAnSthyretin recePtor Amyloid caRdiomyopathy
  NCT06634108 · Phase: Phase 1, Phase 2 · Ages: 40 Years to 80 Years · Sex: All (male and female) · 1 location
• HS235 Study in Obese Participants With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (HFpEF)
  NCT07123779 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure
  NCT07490054 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Levothyroxine Supplementation for Heart Transplant Recipients
  NCT06428097 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Mechanisms of Diuretic Resistance in Heart Failure, Aim 1
  NCT05323487 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Mechanisms of Diuretic Resistance in Heart Failure, Aim 2
  NCT05753059 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Mechanisms of Diuretic Resistance in Heart Failure, Aim 3
  NCT06209359 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction
  NCT06061549 · Phase: Phase 1 · Ages: 50 Years and older · Sex: All (male and female) · 2 locations
• Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
  NCT04703842 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 5 locations
• Novel Approaches for Improving Vascular Function in Veterans With HFpEF
  NCT06312748 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
  NCT06228924 · Phase: Phase 1 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 7 locations
• Peritoneal Ultrafiltration in Cardio Renal Syndrome.
  NCT03994874 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Polypill for Prevention of Cardiomyopathy
  NCT06143566 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 100 Years · Sex: All (male and female) · 1 location
• Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients
  NCT06903559 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Safety and Efficacy of FAP iCDC in End-stage Dilated Cardiomyopathy
  NCT06902896 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Safety and Efficacy of Induced Pluripotent Stem Cell-derived Engineered Human Myocardium as Biological Ventricular Assist Tissue in Terminal Heart Failure
  NCT04396899 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 3 locations
• Safety and Efficacy of Second Infusion of FAP iCDC in End-stage Dilated Cardiomyopathy
  NCT07516288 · Phase: Phase 1 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy
  NCT07172971 · Phase: Phase 1 · Ages: 8 Years to 18 Years · Sex: Male · 1 location
• Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure
  NCT06831825 · Phase: Phase 1 · Ages: 18 Years to 79 Years · Sex: All (male and female) · 1 location
• Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
  NCT06560762 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART)
  NCT06062966 · Phase: Phase 1 · Ages: 21 Years and older · Sex: All (male and female) · 1 location
• Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/Valsartan
  NCT05194111 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 120 Years · Sex: All (male and female) · 1 location
• Vericiguat in Decompensated Cardiac Failure: Clinical Insights on Addition to Guidelines Derived Medical Therapy-VERCIG Trial
  NCT07444398 · Phase: Phase 1 · Ages: 25 Years to 65 Years · Sex: All (male and female) · 1 location

Common questions

What does Phase 1 mean?

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Is this list complete?

No. For the full record, search ClinicalTrials.gov.