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A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission
NCT05719441 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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A Mobile Gaming App to Improve Adherence to PrEP
NCT05762705 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 15 Years to 34 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1
NCT07390955 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies
NCT07569029 ·
Phase: Phase 1 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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ALS Research Collaborative
NCT06885918 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Watertown
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Alcohol and "Heat of the Moment" Sexual Decision Making
NCT05729256 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Male
· Massachusetts: Boston
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Bridge to Belonging: Peer Led Intervention to Reduce Loneliness and Depression Among Older Gay and Bisexual Men
NCT07762066 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
NCT06665646 ·
Phase: Phase 1 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health
NCT06796686 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV
NCT07390474 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1
NCT06071767 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
NCT07473778 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Implementing Depression and Adherence Treatment
NCT07032363 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Improving Coronary Vascular Health in Women
NCT06843902 ·
Phase: Phase 2 ·
Ages: 45 Years to 75 Years ·
Sex: Female
· Massachusetts: Boston
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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)
NCT06263426 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs
NCT07199335 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Menopausal HT for Women Living With HIV (HoT)
NCT06856174 ·
Phase: Phase 4 ·
Ages: 40 Years to 60 Years ·
Sex: Female
· Massachusetts: Boston
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Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV
NCT06001814 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Mitigating the Impact of Stigma and Shame Among People Living With HIV and Substance Use Disorders
NCT05934305 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV
NCT05570812 ·
Phase: Phase 2 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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PrEP and MOUD Rapid Access for Persons Who Inject Drugs: The CHORUS+ Study
NCT05769218 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care
NCT05241990 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Pre-exposure Prophylaxis (PrEP) for Health
NCT04430257 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Cambridge, Lawrence
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Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa
NCT05624931 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 15 Years and older ·
Sex: Female
· Massachusetts: Boston
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Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
NCT06554717 ·
Phase: Phase 2 ·
Ages: 50 Years to 80 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Texting to Reduce Human Immunodeficiency Virus (HIV) Risk
NCT06088277 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission
NCT02140255 ·
Phase: Phase 1, Phase 2 ·
Ages: Up to 48 Hours ·
Sex: All (male and female)
· Massachusetts: Boston