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A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
NCT07218029 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla, Orange, Sacramento, San Francisco
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A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study
NCT07661329 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Beverly Hills, Inglewood, Newport Beach, Petaluma
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A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
NCT07285655 ·
Phase: Phase 3 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Los Angeles, San Francisco
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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Beverly Hills, Canoga Park, Concord, Fremont
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A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
NCT06843577 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years and older ·
Sex: All (male and female)
· California: Valley Village, West Hills
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A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes
NCT06267274 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Bakersfield, Newport Beach
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A Study Evaluating the Safety and Tolerability of Artesunate in Patients With Pulmonary Arterial Hypertension
NCT06872112 ·
Phase: Phase 1 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· California: Stanford
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A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
NCT07142356 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· California: San Jose, West Hills
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A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
NCT07333183 ·
Phase: Phase 2 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· California: Santa Barbara, Torrance
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A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
NCT07175038 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Rancho Cordova
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A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma
NCT06822738 ·
Phase: Phase 3 ·
Ages: 45 Years and older ·
Sex: All (male and female)
· California: Culver City, Petaluma
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A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran
NCT07553442 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Lake Forest
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A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
NCT07481981 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Los Angeles, Santa Barbara, Torrance
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A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
NCT07610278 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Lincoln, Los Angeles, Northridge
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A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
NCT06649110 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· California: Orange, Stanford
-
Acupuncture Therapy and Hypertension
NCT05530512 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· California: Irvine, Orange
-
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
NCT07365332 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Beverly Hills, Santa Barbara, Torrance
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An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH
NCT06129240 ·
Phase: Not specified ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Fresno, La Jolla, Los Angeles, Sacremento
-
Aspirin for Postpartum Patients With Preeclampsia
NCT05924971 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: Female
· California: Long Beach
-
Behavioral Interventions Combining AI/ML and Personalized Medicine to Reduce Cardiovascular Risk - Randomized Controlled Trial
NCT07725250 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla
-
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
NCT05401357 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Newport Beach, Petaluma
-
Blood Pressure Care for Advancing Real-World Evidence (BPCARE)
NCT07398391 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years and older ·
Sex: All (male and female)
· California: San Diego
-
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NCT06059638 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Glendale, Newport Beach, Redwood City, San Diego
-
Chronic Thromboembolic Disease Registry
NCT05843500 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco
-
Clarifying the Optimal Application of SLT Therapy Trial
NCT04967989 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Laguna Hills, Pasadena, Sacramento, San Francisco
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Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
NCT06402968 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· California: Irvine, Lancaster, Palo Alto
-
Data Gathering for A10900
NCT07149740 ·
Phase: Not specified ·
Ages: 22 Years and older ·
Sex: All (male and female)
· California: Anaheim
-
De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
NCT05213676 ·
Phase: Phase 4 ·
Ages: 0 Months to 1 Month ·
Sex: All (male and female)
· California: Irvine, Los Angeles, Palo Alto, San Diego
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DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT06388421 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, Sacramento
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Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope
NCT07136623 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
-
Diagnostic Innovations in Glaucoma Study
NCT00221897 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla
-
Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE)
NCT07322133 ·
Phase: Phase 4 ·
Ages: Up to 28 Days ·
Sex: All (male and female)
· California: Sacramento
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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Beverly Hills, Canoga Park, Concord, Huntington Park
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Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
NCT06526858 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 80 Years ·
Sex: All (male and female)
· California: Orange, Stanford
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Effect of Electro-Acupuncture on Blood Pressure
NCT00932139 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· California: Irvine, Orange
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Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
NCT06468202 ·
Phase: Phase 4 ·
Ages: 14 Years to 35 Years ·
Sex: Female
· California: Los Angeles, San Francisco
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Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT07179380 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, Santa Barbara
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Electrical Stimulation for Vision Neuroenhancement in Glaucoma
NCT06685211 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Palo Alto
-
Electrical Stimulation for the Treatment of Optic Neuropathies
NCT05626426 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Palo Alto
-
Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)
NCT07290244 ·
Phase: Phase 1 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· California: Glendale
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Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
NCT07090161 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· California: Chula Vista, Dublin, Valencia, Walnut Creek
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Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial
NCT05924477 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco, Walnut Creek
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Glaucoma Screening to Enhance At-Risk Californians' Health
NCT06854198 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years and older ·
Sex: All (male and female)
· California: Oakland, San Francisco
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Glaucoma Screening to Enhance At-Risk Californians' Health - Survey Response Incentives
NCT07755748 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years and older ·
Sex: All (male and female)
· California: Oakland, San Francisco
-
Global Paradise System US Post Approval Study
NCT06297291 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Long Beach, Los Angeles, Sacramento, Santa Monica
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Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
NCT06039176 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· California: San Francisco
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Hydrus® Microstent New Enrollment Post-Approval Study
NCT04553523 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years and older ·
Sex: All (male and female)
· California: Irvine, Sacramento
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Hyperbaric Oxygen Therapy for Optic Neuropathies
NCT06128720 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Palo Alto
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LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· California: Sacramento, San Francisco, Stanford, Torrance
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Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication
NCT06876233 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
-
Multi-Omics for Maternal Health After Preeclampsia
NCT06340152 ·
Phase: Not specified ·
Ages: 18 Years to 50 Years ·
Sex: Female
· California: San Diego
-
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
NCT06911632 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Riverside
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Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
NCT06274801 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Fresno, Los Angeles, Sacramento, Stanford
-
Oura Blood Pressure Profile Study
NCT07267871 ·
Phase: Not specified ·
Ages: 22 Years and older ·
Sex: All (male and female)
· California: San Francisco
-
PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy
NCT06915792 ·
Phase: Phase 4 ·
Ages: 18 Years to 64 Years ·
Sex: Female
· California: Los Angeles
-
Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry
NCT02249923 ·
Phase: Not specified ·
Ages: 1 Day to 21 Years ·
Sex: All (male and female)
· California: Palo Alto, San Francisco
-
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· California: Los Angeles, Palo Alto
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Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry
NCT04669548 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, San Francisco
-
Pulmonary Hypertension Association Registry
NCT04071327 ·
Phase: Not specified ·
Ages: 0 Years and older ·
Sex: All (male and female)
· California: Sacramento, San Francisco, Santa Barbara, Stanford
-
REFOCUS-HTN US-WEST: A Data Infrastructure to Characterize Individuals With Hypertension
NCT07780500 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Oakland
-
Reducing Blood Pressure in Patients With High Cardiovascular Risk
NCT05937685 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 35 Years and older ·
Sex: All (male and female)
· California: Downey, Los Angeles, Sylmar, Torrance
-
Right Ventricular Pacing in Pulmonary Arterial Hypertension
NCT04194632 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: San Francisco
-
SPYRAL GEMINI Pilot Study
NCT06907147 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Stanford
-
Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
NCT05551104 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: Female
· California: Loma Linda
-
Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma
NCT07220876 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years and older ·
Sex: All (male and female)
· California: Sacramento
-
Secondhand Tobacco Smoke and Cardiovascular Disease
NCT04715568 ·
Phase: Phase 4 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· California: San Francisco
-
Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation
NCT07354477 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Palo Alto
-
Strategies for Improving Linkage-to-Care After Eye Disease Screening
NCT06943599 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· California: San Francisco
-
Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease
NCT07473700 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: San Francisco
-
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
NCT05587712 ·
Phase: Phase 2 ·
Ages: 1 Year to 17 Years ·
Sex: All (male and female)
· California: Los Angeles, Palo Alto, San Francisco
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THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
NCT06559891 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 75 Years ·
Sex: All (male and female)
· California: Los Angeles, Palo Alto
-
Technology-enabled Management Versus Usual Care for Blood Pressure
NCT05479461 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 30 Years to 90 Years ·
Sex: All (male and female)
· California: Palo Alto
-
To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
NCT06343298 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Beverly Hills, Granada Hills, Lake Forest, Palmdale
-
Topical Insulin for Glaucoma
NCT05206877 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Palo Alto
-
Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications
NCT04354545 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· California: Fountain Valley
-
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
NCT04555161 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla, Los Angeles
-
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Sacramento, San Francisco
-
Village-Integrated Eye Worker Trial II
NCT03752840 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· California: San Francisco
-
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
NCT07181109 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Beverly Hills, Chula Vista, Covina, Escondido