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A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
NCT07218029 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Houston
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A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study
NCT07661329 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston, San Antonio
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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Arlington, Austin, Dallas, Houston
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A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.
NCT07222917 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Arlington, Pasadena, San Antonio
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A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
NCT06843577 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Houston
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A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes
NCT06267274 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
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A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
NCT07142356 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Texas: Bellaire, Dallas, Plano, San Antonio
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A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
NCT07333183 ·
Phase: Phase 2 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Texas: Houston
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A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
NCT07175038 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Houston
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A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma
NCT06822738 ·
Phase: Phase 3 ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Texas: Dallas, El Paso, Houston
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A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
NCT07610278 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Houston
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A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
NCT06649110 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Texas: Austin, Dallas
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An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
NCT07365332 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Dallas
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An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH
NCT06129240 ·
Phase: Not specified ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Houston
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Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions
NCT05168605 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· Texas: Dallas
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Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
NCT05401357 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Houston
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Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients
NCT04163614 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas
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BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NCT06059638 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Dallas
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Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma
NCT05564091 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Texas: Sugar Land
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Change in IOP Fluctuation After DSLT
NCT07428668 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Fort Worth
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Clarifying the Optimal Application of SLT Therapy Trial
NCT04967989 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Fort Worth
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Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
NCT06402968 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Texas: Dallas, San Antonio
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Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults
NCT05955339 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Galveston
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De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
NCT05213676 ·
Phase: Phase 4 ·
Ages: 0 Months to 1 Month ·
Sex: All (male and female)
· Texas: Houston
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DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT06388421 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Houston
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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Brownsville, Dallas, El Paso
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Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
NCT06468202 ·
Phase: Phase 4 ·
Ages: 14 Years to 35 Years ·
Sex: Female
· Texas: Houston
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Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
NCT07090161 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Texas: Carrollton
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Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)
NCT07218783 ·
Phase: Phase 3 ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Texas: Houston
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Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
NCT07218796 ·
Phase: Phase 3 ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Texas: San Antonio
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External Lumbar Drainage to Reduce ICP in Severe TBI: a Phase 1 Clinical Trial
NCT05889650 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Texas: Dallas, Fort Sam Houston, Houston, San Antonio
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Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH
NCT03980717 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 45 Years ·
Sex: Female
· Texas: Houston
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Global Paradise System US Post Approval Study
NCT06297291 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Dallas, Kingwood
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Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies
NCT07659821 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 45 Years ·
Sex: Female
· Texas: College Station, Dallas, Mansfield
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Hydrus® Microstent New Enrollment Post-Approval Study
NCT04553523 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Texas: Austin, Dallas, El Paso, Hurst
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IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine
NCT06218355 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female
· Texas: Dallas
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LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Texas: Austin, Dallas, El Paso, Houston
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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
NCT06911632 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Houston
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Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial
NCT05844384 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Lackland Air Force Base
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Non-Invasive Preeclampsia Screening and Biobank
NCT06643741 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: Female
· Texas: Austin, Galveston, Houston
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Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
NCT06274801 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Dallas, Houston, San Antonio
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PRESSURE CHECK: Find Your Path to Better Health
NCT06122246 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
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Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry
NCT02249923 ·
Phase: Not specified ·
Ages: 1 Day to 21 Years ·
Sex: All (male and female)
· Texas: Houston
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· Texas: Austin, Dallas, Houston
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Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
NCT07075718 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: El Paso
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Polypill for Prevention of Cardiomyopathy
NCT06143566 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Texas: Dallas
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Predict Severe Traumatic Brain Injury
NCT06966713 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
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Preventing Cognitive Decline by Reducing BP Target Trial
NCT05106036 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 70 Years and older ·
Sex: All (male and female)
· Texas: Dallas
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Pulmonary Hypertension Association Registry
NCT04071327 ·
Phase: Not specified ·
Ages: 0 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Houston, Plano
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Rocklatan vs Latanoprost Post-DSLT
NCT07465913 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Beaumont
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SPYRAL GEMINI Pilot Study
NCT06907147 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Dallas, Tyler
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Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy
NCT06313749 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· Texas: Dallas
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Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma
NCT07220876 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Texas: Dallas
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Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension
NCT07511361 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Laredo, Paris, Temple
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Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
NCT04838678 ·
Phase: Early Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Texas: Dallas
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THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
NCT06559891 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 75 Years ·
Sex: All (male and female)
· Texas: Fort Worth, Houston
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Targeting Endoplasmic Reticulum Stress in Human Hypertension
NCT06025630 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Fort Worth
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The "Check, Monitor, Control Hypertension" Study is a 24-month Randomized Trial in Houston Targeting African Americans Aged 55+. It Combines Pharmacist Counseling and CHW Support to Improve Blood Pressure Control in Hypertension Management.
NCT07413159 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Texas: Houston
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To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
NCT06343298 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Coppell, Dallas, Houston, Mansfield
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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Dallas, Houston, Plano
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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
NCT07181109 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Allen, Amarillo, Arlington, Austin
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iDose TR Administration in an Office-Based Surgery Setting
NCT07816692 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin