Clinical trials recruiting for Lynch Syndrome

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
  NCT05411718 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule
  NCT07219537 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire
  NCT07194551 · Phase: Not applicable (e.g. observational or device study) · Ages: 30 Years and older · Sex: Female · 1 location
• CAD-EYE System for the Detection of Neoplastic Lesions in Patients With Lynch Syndrome
  NCT05963191 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 90 Years · Sex: All (male and female) · 1 location
• Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland
  NCT03124212 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 9 locations
• Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch Syndrome
  NCT07201012 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Familial Investigations of Childhood Cancer Predisposition
  NCT03050268 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• First in Human Pilot Study to Assess the Safety and Efficacy of Dendritic Cells Loaded With Frameshift Derived Neopeptides for the Prevention of Cancer in of Lynch Syndrome Carriers
  NCT07163403 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients
  NCT06523582 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Identifying and Caring for Individuals With Inherited Cancer Syndrome
  NCT04494945 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Impact of Consumption of Ultra-processed Foods in Individuals at High Risk of Cancer
  NCT07436312 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
  NCT07106359 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Integrated Cancer Repository for Cancer Research
  NCT02012699 · Phase: Not specified · Ages: 19 Years to 110 Years · Sex: All (male and female) · 84 locations
• Liquid Biopsy Evaluation and Repository Development at Princess Margaret
  NCT03702309 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection
  NCT07450612 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Lynch Syndrome Integrative Epidemiology and Genetics
  NCT06582914 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Lynch Syndrome X-Talk of Enteral Mucosa With Immune System
  NCT06708429 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 5 locations
• Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome
  NCT07220239 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: Female · 1 location
• Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome
  NCT04920149 · Phase: Phase 2 · Ages: 30 Years and older · Sex: All (male and female) · 8 locations
• Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal Cancer
  NCT05495776 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Prostate Cancer Genetic Risk Evaluation and Screening Study
  NCT05129605 · Phase: Not specified · Ages: 35 Years to 74 Years · Sex: Male · 1 location
• Registry of Subjects at Risk of Pancreatic Cancer
  NCT04095195 · Phase: Not specified · Ages: 18 Years to 80 Years · Sex: All (male and female) · 4 locations
• Small Bowel Capsule Endoscopy in Lynch Syndrome
  NCT07472686 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• The Cancer of the Pancreas Screening-5 CAPS5)Study
  NCT02000089 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 9 locations
• The GEOLynch Cohort Study
  NCT03303833 · Phase: Not specified · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study)
  NCT06218433 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 75 Years · Sex: All (male and female) · 2 locations
• Video Capsule Examination in Patients With Lynch Syndrome
  NCT06712095 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Videocapsule Endoscopy in Lynch Syndrome
  NCT05704010 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Lynch Syndrome often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Lynch Syndrome trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.