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A Beta-only IL-2 ImmunoTherapY Study
NCT05086692 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Diego, San Francisco, Santa Monica
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A Phase 1 Study of LNCB74 in Advanced Solid Tumors
NCT06774963 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Newport Beach
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A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
NCT07109726 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Duarte, Irvine
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A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
NCT06586957 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, San Francisco
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A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
NCT04657068 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, Santa Barbara, Santa Rosa
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A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
NCT06778863 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, Sacramento, San Francisco
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A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
NCT05377996 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Orange, San Francisco, Santa Monica
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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
NCT06465069 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Duarte, La Jolla, Los Angeles
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A Study of MGC026 in Participants With Advanced Solid Tumors
NCT06242470 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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A Study of MT-4561 in Patients With Various Advanced Solid Tumors
NCT06943521 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
NCT05877599 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Duarte, Los Angeles, Newport Beach, Santa Monica
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A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
NCT06051695 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla, Los Angeles, Stanford
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A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
NCT04503265 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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AOH1996 for the Treatment of Refractory Solid Tumors
NCT05227326 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Duarte, Long Beach
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BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)
NCT04752826 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Duarte
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DESTINY-PANTUMOUR04
NCT07124000 ·
Phase: Not specified ·
Ages: 18 Years to 130 Years ·
Sex: All (male and female)
· California: San Diego
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Distance-Based Exercise to Preserve Function and Prevent Disability
NCT07059884 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Dublin, Fremont, Fresno, Modesto
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Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors
NCT07517198 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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EXoPERT EMERALD Clinical Study
NCT07186296 ·
Phase: Not specified ·
Ages: 45 Years and older ·
Sex: All (male and female)
· California: Long Beach, Los Angeles
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Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
NCT05983432 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Beverly Hills, Duarte, Irvine, Orange
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FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
NCT07216105 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla, Los Angeles
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Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples
NCT01034033 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: Female
· California: Stanford
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Navigation Intervention for Adolescent and Young Adult Cancer Survivors
NCT07406087 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years to 45 Years ·
Sex: All (male and female)
· California: Pasadena
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Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
NCT06293898 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Duarte, Los Angeles, San Diego
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Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
NCT06580002 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Orange
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Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
NCT07447050 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Orange
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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
NCT03452774 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· California: Duarte, Irvine, La Jolla, Orange
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Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
NCT06582017 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, Newport
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Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
NCT04981119 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Duarte, La Jolla, Palo Alto, Santa Monica
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Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors
NCT07444814 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
NCT05489211 ·
Phase: Phase 2 ·
Ages: 18 Years to 130 Years ·
Sex: All (male and female)
· California: Los Angeles, San Diego, Santa Rosa
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Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
NCT06545942 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla, San Francisco
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Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors
NCT07524322 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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TT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural Mesothelioma
NCT04969315 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
NCT04585750 ·
Phase: Phase 1, Phase 2 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· California: Irvine, La Jolla, Los Angeles
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Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
NCT07064018 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Orange
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cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
NCT05366881 ·
Phase: Not specified ·
Ages: 40 Years and older ·
Sex: All (male and female)
· California: Duarte