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A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
NCT06680830 ·
Phase: Phase 2 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· California: Fresno, Irvine, Los Angeles, Murrieta
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A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)
NCT06285643 ·
Phase: Phase 2 ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· California: Irvine, Loma Linda, San Francisco
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A Study of Buntanetap in Participants With PD
NCT07284784 ·
Phase: Phase 2, Phase 3 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· California: Fountain Valley
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A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
NCT06765668 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Aliso Viejo, Palo Alto
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A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
NCT06809400 ·
Phase: Phase 1 ·
Ages: 30 Years to 85 Years ·
Sex: All (male and female)
· California: Los Alamitos
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A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
NCT06976268 ·
Phase: Phase 2, Phase 3 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· California: Irvine, Los Angeles
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A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
NCT07432958 ·
Phase: Phase 2 ·
Ages: 30 Years to 80 Years ·
Sex: All (male and female)
· California: Carlsbad, Los Alamitos, Los Angeles, Palo Alto
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A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
NCT07174310 ·
Phase: Phase 3 ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female)
· California: Fullerton, La Jolla, Los Angeles, Palo Alto
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A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy
NCT07804615 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· California: Murrieta
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A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
NCT06944522 ·
Phase: Phase 3 ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· California: Los Angeles, Orange, Palo Alto
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A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
NCT07330258 ·
Phase: Not specified ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· California: Fountain Valley, Los Angeles
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Automated Daytime Adaptive Deep Brain Stimulation Parameter Optimization in Patients Implanted With Percept Neurostimulator
NCT07682311 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 25 Years to 75 Years ·
Sex: All (male and female)
· California: San Francisco
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Combined STN and NBM Deep Brain Stimulation for Mild Cognitive Impairment in Parkinson's Disease
NCT05968703 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years to 80 Years ·
Sex: All (male and female)
· California: Stanford
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Dual Frequency Stimulation in Parkinson's Disease
NCT04650932 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Sacramento
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Effects of Accelerated rTMS On Motor and Cognitive Function in Parkinson's Disease
NCT07554833 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years to 90 Years ·
Sex: All (male and female)
· California: San Francisco
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Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease
NCT07207122 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 80 Years ·
Sex: All (male and female)
· California: Santa Monica
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Evaluation of Neurocognitive Changes in Parkinson's Disease After Low Frequency Burst Stimulation
NCT05307055 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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GBPDC: Gut-Brain in PD Consortium Master Protocol
NCT07567794 ·
Phase: Not specified ·
Ages: 21 Years to 80 Years ·
Sex: All (male and female)
· California: Stanford
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Ketamine for Veterans With Parkinson's Disease
NCT06231563 ·
Phase: Phase 2 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· California: San Francisco
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Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease
NCT07005180 ·
Phase: Phase 2 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· California: Fountain Valley
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Optimizing Adaptive DBS for Parkinson's Disease
NCT07798271 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Davis
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PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
NCT04477785 ·
Phase: Not specified ·
Ages: 30 Years and older ·
Sex: All (male and female)
· California: La Jolla, Los Angeles, San Francisco
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Parkinson Progression Marker Initiative Online (PPMI Online)
NCT05065060 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco
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Parkinson's Foundation PD GENEration Genetic Registry
NCT04994015 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla, Los Angeles, Redwood City, San Francisco
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Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
NCT04373317 ·
Phase: Phase 4 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· California: Loma Linda, Palo Alto, San Francisco, West Los Angeles
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Psilocybin Therapy for Depression in Parkinson's Disease
NCT06455293 ·
Phase: Phase 2 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· California: San Francisco
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Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States:
NCT07219927 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Aliso Viejo, Irvine, Palo Alto
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Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
NCT02071134 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Aliso Viejo, Los Angeles
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Safety and Usability of the Cionic Neural Sleeve for Parkinson's Disease
NCT07284823 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 75 Years ·
Sex: All (male and female)
· California: Carlsbad, San Francisco
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Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
NCT05395624 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: San Francisco, Stanford
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Safety, Tolerability and Exploratory Efficacy of EC5026 in Parkinson's Disease (STEP Study)
NCT07142044 ·
Phase: Phase 1, Phase 2 ·
Ages: 50 Years to 80 Years ·
Sex: All (male and female)
· California: Sacramento
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Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease
NCT07398157 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco
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Title: A Multimodal Exercise Program With Gamification for Parkinson Disease (MEP+G)
NCT06538298 ·
Phase: Early Phase 1 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· California: Ventura
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Transplantation of Human iPS Cell-derived Dopaminergic Progenitors (CT1-DAP001) for Parkinson's Disease (Phase I/II)
NCT06482268 ·
Phase: Phase 1 ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female)
· California: La Jolla
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Understanding Motivation in Parkinson's Patients Through Neurophysiology
NCT05065151 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco
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Use of CereGate Therapy for Freezing of Gait in PD
NCT05292794 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years to 80 Years ·
Sex: All (male and female)
· California: Redwood City