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A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
NCT06680830 ·
Phase: Phase 2 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Ohio: Columbus
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A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease
NCT04991831 ·
Phase: Not specified ·
Ages: 30 Years to 99 Years ·
Sex: All (male and female)
· Ohio: Cleveland, Fairborn
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A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)
NCT06285643 ·
Phase: Phase 2 ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· Ohio: Columbus
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A Study of Buntanetap in Participants With PD
NCT07284784 ·
Phase: Phase 2, Phase 3 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· Ohio: Columbus
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A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
NCT06765668 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Ohio: Canton, Cincinnati, Cleveland
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A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
NCT07432958 ·
Phase: Phase 2 ·
Ages: 30 Years to 80 Years ·
Sex: All (male and female)
· Ohio: Cleveland, Columbus
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A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
NCT07174310 ·
Phase: Phase 3 ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female)
· Ohio: Canton, Cleveland
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A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy
NCT07804615 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Ohio: Canton
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A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
NCT06944522 ·
Phase: Phase 3 ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· Ohio: Toledo
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A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
NCT07330258 ·
Phase: Not specified ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· Ohio: Cleveland
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BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease
NCT07138560 ·
Phase: Phase 4 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Ohio: Cleveland
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Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
NCT06719583 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Ohio: Cleveland
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Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease
NCT07110376 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Ohio: Cleveland
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Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease
NCT05400499 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Ohio: Cleveland
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Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease
NCT03019757 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Ohio: Columbus
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Genetics and Aerobic Exercise to Slow Parkinson's Disease Trial
NCT06442033 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Ohio: Cleveland
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Neural Mechanisms of Aerobic Exercise Benefits in PD With DBS
NCT07442747 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Ohio: Cleveland
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Optimizing Deep Brain Stimulation to Improve Visuomotor Function in Parkinson's Disease
NCT06857851 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Ohio: Cleveland
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PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
NCT04477785 ·
Phase: Not specified ·
Ages: 30 Years and older ·
Sex: All (male and female)
· Ohio: Cincinnati, Cleveland
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Parkinson's Foundation PD GENEration Genetic Registry
NCT04994015 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Ohio: Cincinnati, Cleveland, Colombus
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Personalized Real-Time DBS and PD Mechanisms
NCT06013956 ·
Phase: Phase 4 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Ohio: Cleveland
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Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
NCT04373317 ·
Phase: Phase 4 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Ohio: Cleveland
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Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
NCT02071134 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Ohio: Cleveland, Columbus
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The Parkinson's Genetic Research Study
NCT01558479 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Ohio: Cincinnati
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Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms
NCT07182058 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Ohio: Cleveland