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A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
NCT07351045 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, Needham
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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
NCT07662135 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Braintree, New Bedford, Worcester
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A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
NCT07662109 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
NCT06112418 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
NCT07415954 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
NCT04786262 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
NCT07654374 ·
Phase: Phase 3 ·
Ages: 18 Years to 79 Years ·
Sex: All (male and female)
· Massachusetts: Methuen
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A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
NCT07340320 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Massachusetts: Springfield
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A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
NCT07282600 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: New Bedford
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A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
NCT07321886 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Quincy
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A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
NCT07392190 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, Waltham
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A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
NCT07589608 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Massachusetts: Needham, New Bedford
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AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
NCT07797335 ·
Phase: Phase 3 ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems
NCT06959277 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Boosting Emotional Well-being and Happiness in Outpatients Living With Diabetes
NCT05420051 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Continuous Glucose Monitor Use in Pregnancy
NCT05317585 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female
· Massachusetts: Worcester
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DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
NCT06525259 ·
Phase: Not specified ·
Ages: 8 Years to 15 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Diabetes Body Project 2
NCT07468188 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 40 Years ·
Sex: Female
· Massachusetts: Boston
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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Malden, Methuen
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EVOC - EVs in Obesity and Cardiometabolic Disease
NCT06408961 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
NCT06138821 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System
NCT07579702 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 14 Years to 75 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes
NCT07521475 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH
NCT06003153 ·
Phase: Phase 4 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Gastroparesis Registry 4
NCT05846802 ·
Phase: Not specified ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)
NCT06251323 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Improving Coronary Vascular Health in Women
NCT06843902 ·
Phase: Phase 2 ·
Ages: 45 Years to 75 Years ·
Sex: Female
· Massachusetts: Boston
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Improving Diabetes Care With Strategies For Addressing Health-Related Social Needs and Community Partnerships
NCT07043426 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
NCT06451757 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population
NCT05799222 ·
Phase: Not specified ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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NAD Augmentation in Diabetes Kidney Disease
NCT05759468 ·
Phase: Phase 2 ·
Ages: 30 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Nutrition+: Effect of a High-Protein Diabetes Formula on Body Composition in Type 2 Diabetes Patients Treated With Incretin Mimetics
NCT07271043 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
NCT05390892 ·
Phase: Phase 4 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Massachusetts: Boston, Worcester
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Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery
NCT07011147 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 89 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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RESET System Pivotal Trial (Rev F)
NCT04101669 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Re-Engineered Discharge for Diabetes Care Transitions
NCT06869057 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Worcester
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Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
NCT07296484 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Springfield
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Vitamin D and Type 2 Diabetes - Treat-To-Target
NCT07448974 ·
Phase: Phase 3 ·
Ages: 30 Years to 74 Years ·
Sex: All (male and female)
· Massachusetts: Boston