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A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
NCT07351045 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: West Chester
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A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
NCT07351058 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
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A Fruit and Vegetable Prescription Program
NCT06107816 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Reading
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A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
NCT07667803 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: DuBois, Newport, Philadelphia
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A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
NCT06112418 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Pennsylvania: Camp Hill
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A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes
NCT07061574 ·
Phase: Phase 1, Phase 2 ·
Ages: 9 Years to 20 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
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A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
NCT07668388 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Pennsylvania: Uniontown
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A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
NCT07564414 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Beaver, Hatboro, Philadelphia
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A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
NCT07282613 ·
Phase: Phase 3 ·
Ages: 10 Years to 18 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
NCT04786262 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia, Pittsburgh
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A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
NCT07654374 ·
Phase: Phase 3 ·
Ages: 18 Years to 79 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
NCT06739122 ·
Phase: Phase 3 ·
Ages: 10 Years to 17 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
NCT07282600 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh, Uniontown
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A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
NCT07321886 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Uniontown
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A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
NCT07392190 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
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A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
NCT06897475 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Pennsylvania: Scottdale
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A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
NCT07743450 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia, Pittsburgh
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A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
NCT07776509 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Smithfield
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A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
NCT07784725 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia, Smithfield
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A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
NCT07662213 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Feasterville-Trevose, Philadelphia
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A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
NCT07754461 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Beaver, Pittsburgh, Uniontown
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AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
NCT07797335 ·
Phase: Phase 3 ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Pennsylvania: Beaver, Newport
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Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems
NCT06959277 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
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Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
NCT05277558 ·
Phase: Not specified ·
Ages: 12 Years to 17 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
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CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes
NCT07184775 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female
· Pennsylvania: Philadelphia
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CGM for Management of Type 2 Diabetes in Pregnancy
NCT06628453 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 50 Years ·
Sex: Female
· Pennsylvania: Philadelphia
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DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
NCT06525259 ·
Phase: Not specified ·
Ages: 8 Years to 15 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Beaver, Camp Hill, Philadelphia, Pittsburgh
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Gastroparesis Registry 4
NCT05846802 ·
Phase: Not specified ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Impact of a Diabetes Education Mobile Web Application on Patients With Uncontrolled Type 2 Diabetes
NCT05893927 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: West Reading
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Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs
NCT06600724 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Monroeville
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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
NCT05390892 ·
Phase: Phase 4 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Pennsylvania: Danville, Philadelphia
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Pharmacogenetics of Response to GLP1R Agonists
NCT05071898 ·
Phase: Phase 1 ·
Ages: 18 Years to 89 Years ·
Sex: All (male and female)
· Pennsylvania: Lancaster
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Phenotyping Genetic Risk for Type 2 Diabetes
NCT04024631 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 10 Years to 70 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Pilot-Testing Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes
NCT07270016 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 16 Years to 24 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
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Pilot-Testing Strategies to Improve Outcomes for Youth With Type 2 Diabetes by Addressing Health-Related Social Needs
NCT07216118 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 13 Years and older ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
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Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG
NCT07216391 ·
Phase: Phase 2 ·
Ages: 4 Years to 34 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
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Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy
NCT07086443 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Monroeville
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Registry for Stage 2 Type 1 Diabetes
NCT06481904 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Sleep and Glycemic Control in Type 2 Diabetes Adolescents
NCT04213547 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 20 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
NCT07271186 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Pennsylvania: Bethlehem, West Chester
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The GRoceries Aimed at Increasing Nutrition Study
NCT07167004 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years to 70 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Transformative Research in Diabetic Nephropathy 2.0
NCT07444203 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
NCT07296484 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: West Chester