Phase 4 Type 2 diabetes trials recruiting now

All Type 2 diabetes trials, every phase

Other phases for Type 2 diabetes

Phase 4 Type 2 diabetes trials

• A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers
  NCT07159282 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Phase IV Clinical Trial to Compare the Efficacy and Safety of Metformin+Sodium-Glucose Cotransporter 2 Inhibitor(SGLT2-i)+Thiazolidinedione (TZD) in Patients With Type 2 Diabetes
  NCT06972732 · Phase: Phase 4 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• A Pragmatic Trial Comparing Empagliflozin and Dapagliflozin Through Cluster Randomization Embedded in the Electronic Health Record
  NCT06642272 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 12 locations
• A Prospective Trial of Enavogliflozin to Evaluate Cardio-renal Outcome in Type 2 Diabetes Mellitus Patients
  NCT06642623 · Phase: Phase 4 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels Compared to Daily Basal Insulins in Adults With Type 2 Diabetes
  NCT07112339 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 75 locations
• A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)
  NCT07247084 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 30 locations
• Atmeg (Atorvastatin and Omega-3 Combination) and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia
  NCT05365438 · Phase: Phase 4 · Ages: 20 Years to 80 Years · Sex: All (male and female) · 1 location
• Choline Fenofibrate and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia
  NCT05365425 · Phase: Phase 4 · Ages: 20 Years and older · Sex: All (male and female) · 1 location
• Cilostazol and Aspirin for Cardiovascular Event Prevention in Patients With Type 2 Diabetes
  NCT07719894 · Phase: Phase 4 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• Clopidogrel Versus Cilostazol on Vessels
  NCT06402747 · Phase: Phase 4 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• Cofrogliptin Once Every 2 Weeks as Add-on Therapy to Metformin and Dapagliflozin Versus Daily Linagliptin in Patients With Type 2 Diabetes.
  NCT07019012 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• DM Treatment to Evaluate the Efficacy and Safety of Dapagliflozin or Pioglitazone in Patients with Type 2 Diabetes
  NCT06875193 · Phase: Phase 4 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes
  NCT06983054 · Phase: Phase 4 · Ages: 18 Years to 85 Years · Sex: All (male and female) · 2 locations
• Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in Individuals With Type 2 Diabetes
  NCT06613854 · Phase: Phase 4 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Effect of Empagliflozin on Quality of Life in Chronic Heart Failure Patients With Diabetes Mellitus Type II
  NCT06706791 · Phase: Phase 4 · Ages: 40 Years to 70 Years · Sex: All (male and female) · 1 location
• Effect of Erugliflozin On Liver Fat, Liver Fibrosis and Glycemic Control in Type II DM Patients With NASH/NAFLD
  NCT05644717 · Phase: Phase 4 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)
  NCT03883412 · Phase: Phase 4 · Ages: 21 Years to 60 Years · Sex: All (male and female) · 1 location
• Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes
  NCT07558863 · Phase: Phase 4 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Effect of Henagliflozein on Hepatic Fat Content in Patients With T2DM and NAFLD
  NCT06449833 · Phase: Phase 4 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Effect of Tirzepatide on Progression of Coronary Atherosclerosis Using MDCT
  NCT05708859 · Phase: Phase 4 · Ages: 40 Years to 80 Years · Sex: All (male and female) · 1 location
• Effect of Treatment With Finerenone on Cardio-Renal Target Organ Damage in Patients With Type 2 Diabetes.
  NCT07026539 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome
  NCT06410352 · Phase: Phase 4 · Ages: 35 Years to 65 Years · Sex: All (male and female) · 1 location
• Effects of Enavogliflozin on Coronary Microvascular and Cardiac Function in Obesity
  NCT06782139 · Phase: Phase 4 · Ages: 20 Years to 79 Years · Sex: All (male and female) · 1 location
• Effects of Semaglutide on Clinical Outcomes and Metabolic Inflammation in Psoriasis
  NCT07401992 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Effects of Semaglutide on Intracranial Blood Flow and Brain-Barrier Permeability in Type-2 Diabetes
  NCT05780905 · Phase: Phase 4 · Ages: 40 Years to 65 Years · Sex: All (male and female) · 1 location
• Effects of Tirzepatide and Insulin Glargine on Glucolipid Metabolism and Brain Function in Patients With Type 2 Diabetes
  NCT05553093 · Phase: Phase 4 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Efficacy and Safety of Canagliflozin in the Treatment of Type 2 Diabetes With Mild Cognitive Impairment
  NCT07711171 · Phase: Phase 4 · Ages: 40 Years to 75 Years · Sex: All (male and female) · 1 location
• Efficacy and Safety of Henagliflozin Proline and Metformin Hydrochloride Extended-release Tablets (Ⅰ) Versus Metformin Tablets in Patients With New-onset Type 2 Diabetes: a Multicenter, Randomized Controlled Study
  NCT06888050 · Phase: Phase 4 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Efficacy and Safety of iGlarLixi Versus Standard of Care in a Real-world Adult China Population With Uncontrolled Type 2 Diabetes on Oral Agents
  NCT07307235 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 24 locations
• Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control
  NCT07244003 · Phase: Phase 4 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay.
  NCT07588438 · Phase: Phase 4 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 2 locations
• Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis
  NCT06399835 · Phase: Phase 4 · Ages: 20 Years to 80 Years · Sex: All (male and female) · 1 location
• Fingolimod for Type 2 Diabetes Mellitus
  NCT05307731 · Phase: Phase 4 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM
  NCT07314684 · Phase: Phase 4 · Ages: 18 Years to 85 Years · Sex: All (male and female) · 2 locations
• GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH
  NCT06003153 · Phase: Phase 4 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis
  NCT07017270 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Glycemic Control With Triple Pathway Approach Through Empagliflozin, Linagliptin and Metformin Combination
  NCT06862739 · Phase: Phase 4 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 2 locations
• Glycemic Variability of Combination Therapies in T2DM
  NCT07442006 · Phase: Phase 4 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes
  NCT06706284 · Phase: Phase 4 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 2 locations
• High Dose Aflibercept in Diabetic Macular Edema in Patients With Previous Vitrectomy
  NCT06662994 · Phase: Phase 4 · Ages: 21 Years and older · Sex: All (male and female) · 1 location
• Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes
  NCT03264352 · Phase: Phase 4 · Ages: 45 Years to 79 Years · Sex: All (male and female) · 1 location
• Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes
  NCT06478186 · Phase: Phase 4 · Ages: 40 Years and older · Sex: All (male and female) · 2 locations
• Liraglutide-bolus vs Glargine-bolus Therapy in Overweight/Obese Type 2 Diabetes Patients (LiraGooD)
  NCT03087032 · Phase: Phase 4 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Low-Dose Semaglutide for Weight Loss in Obese Non-Diabetic Pakistani Adults
  NCT07513168 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Mechanism of SGLT2 Inhibition in the Kidney
  NCT06291155 · Phase: Phase 4 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Metformin Hydrochloride Sustained-release Tablets (Ⅲ) in Patients With Type 2 Diabetes Mellitus Complicated With Coronary Heart Disease
  NCT06932874 · Phase: Phase 4 · Ages: 30 Years to 75 Years · Sex: All (male and female) · 1 location
• Modeling Ketosis-Prone Diabetes Remission Via Diverse Mechanisms of Glucotoxicity
  NCT06699810 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• NT-proBNP Selected Prevention of Cardiac Events in Diabetic Patients
  NCT02817360 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 21 locations
• Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide
  NCT06657209 · Phase: Phase 4 · Ages: 30 Years to 70 Years · Sex: All (male and female) · 2 locations
• PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
  NCT05390892 · Phase: Phase 4 · Ages: 40 Years to 80 Years · Sex: All (male and female) · 36 locations
• Pioglitazone and Empagliflozin for Fatty Liver Disease in Type 2 Diabetes
  NCT06989723 · Phase: Phase 4 · Ages: 20 Years and older · Sex: All (male and female) · 1 location
• Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants
  NCT05838287 · Phase: Phase 4 · Ages: 30 Years to 70 Years · Sex: All (male and female) · 1 location
• Quantifying Hepatic Mitochondrial Fluxes in Humans
  NCT05305287 · Phase: Phase 4 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 2 locations
• Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy
  NCT07086443 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study
  NCT05164263 · Phase: Phase 4 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 6 locations
• SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue in Diabetes
  NCT07614230 · Phase: Phase 4 · Ages: 18 Years to 78 Years · Sex: All (male and female) · 2 locations
• Screening and Intervention for Subclinical Coronary Artery Disease in Patients With Type 2 Diabetes
  NCT05700877 · Phase: Phase 4 · Ages: 55 Years to 75 Years · Sex: All (male and female) · 1 location
• The Ameliorative Effects of GLP-1RA on Diabetic Cardiac Autonomatic Neuropathy
  NCT06461377 · Phase: Phase 4 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• The EMPA-FIT Study
  NCT06846411 · Phase: Phase 4 · Ages: 20 Years and older · Sex: All (male and female) · 1 location
• The Effect of Empagliflozin and Metformin on Oxidative Capacity and Microvascular Reactivity of Skeletal Muscle in Patients With Type 2 Diabetes Mellitus
  NCT07771010 · Phase: Phase 4 · Ages: 18 Years to 75 Years · Sex: Male · 1 location
• The Effect of Gliatamin (Chonline Alphoscerate) on Depressive Mood in Type 2 Diabetes Patients
  NCT03059069 · Phase: Phase 4 · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• The Effect of Propolis Administration on Cholesterol Level in Diabetic Type 2 Patients
  NCT06903546 · Phase: Phase 4 · Ages: 35 Years to 59 Years · Sex: All (male and female) · 1 location
• The Effects of Henagliflozin on Glucose Fluctuation and Immunosenescence in Type 2 Diabetes Patients on Insulin Therapy
  NCT06818851 · Phase: Phase 4 · Ages: 50 Years to 70 Years · Sex: All (male and female) · 1 location
• The Impact of Semaglutide Compared to Energy Restriction on Type 2 Diabetes
  NCT07272343 · Phase: Phase 4 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Use of Clinical-trials and Simulation Models to Estimate Cost-effectiveness of Non-steroidal Mineralocorticoid Antagonists, RASi and SGLT2i as Triple Therapy With Type 2 Diabetes and Chronic Kidney Disease
  NCT06727409 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• iGlarLixi CGM Study in Chinese T2D Individuals After OADs
  NCT06671587 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location

Common questions

What does Phase 4 mean?

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Is this list complete?

No. For the full record, search ClinicalTrials.gov.