Amygdala Memory Enhancement
Recruiting · NCT05065450 · Interventional (participants receive a specific treatment) · Lead sponsor: Washington University School of Medicine
View the official record on ClinicalTrials.gov →Interventions studied
Intracranial Stimulation
What this trial is about
The objective is to understand how amygdala activation affects other medial temporal lobe structures to prioritize long-term memories. The project is relevant to disorders of memory and to disorders involving affect and memory, including traumatic brain injury and post-traumatic stress disorder.
Who can take part
Age range
18 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Must be able to understand and speak English.
- Able to provide informed consent.
- Diagnosed with epilepsy.
- Scheduled to undergo long-term intra-cranial video monitoring for seizure onset localization.
- Must be implanted with intracranial depth electrodes to the left or right amygdala, hippocampus, and parahippocampal/perirhinal cortices.
Exclusion criteria
- Unable to understand and speak English.
- Unable to provide informed consent.
- Not diagnosed with epilepsy.
Where it is running
1 location listed across 1 US state.
- Washington University School of Medicine - St Louis, Missouri, United States