Taiwan Post-Stroke Disability Study
Recruiting · NCT06772194 · Observational (researchers observe without assigning treatment) · Lead sponsor: National Taiwan University Hospital
View the official record on ClinicalTrials.gov →What this trial is about
Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range of disabilities in areas such as motor function, swallowing, cognition, depression, and epilepsy. This study will investigate these disabilities by enrolling 2,000 acute stroke patients (both ischemic and hemorrhagic) from 10 medical centers across Taiwan. Data will be collected at three key points: at enrollment, three months, and twelve months post-stroke, using surveys, assessments, imaging, and blood samples. The aim is to examine the prevalence, risk factors, and long-term changes of post-stroke disabilities, ultimately seeking ways to reduce the health burden of stroke in Taiwan.
Who can take part
Inclusion criteria
- Ischemic stroke confirmed by MRI, or hemorrhagic stroke diagnosed by CT or MRI.
- Age ≥ 18 years.
- Pre-stroke modified Rankin Scale (mRS) score of 0, 1, or 2.
- Post-stroke mRS score of 0, 1, 2, 3, or 4 at enrollment.
- Able to undergo cognitive function screening and other scale assessments within 30 days post-stroke.
Exclusion criteria
- Transient ischemic stroke and subarachnoid hemorrhage.
- Clear and severe psychiatric or emotional disorders before the stroke, including schizophrenia, major depressive disorder, and bipolar disorder.
- History of clinical stroke within three months prior to enrollment.
- Unable to communicate or cooperate for assessments due to severe aphasia.
- Severe dementia prior to the stroke.
- Pre-stroke modified Rankin Scale (mRS) score ≥ 3.
- Post-stroke mRS score of 5 at enrollment.
- History of cancer with an expected life expectancy of less than one year.
- Expected life expectancy of less than one year due to other medical conditions.
- Anticipated inability to complete a one-year follow-up.
- Other situations deemed unsuitable for enrollment by the clinical investigator.
Where it is running
1 location listed.
- National Taiwan University Hospital, Taipei, - Taipei, Taiwan