Colorectal cancer trials recruiting in Ohio

All Colorectal cancer trials nationally

Cities in Ohio

Recruiting trials in Ohio

• 64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer
  NCT06298916 · Phase: Phase 1, Phase 2 · Ages: 15 Years and older · Sex: All (male and female) · Ohio: Cincinnati
• A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients
  NCT06424522 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer
  NCT07079631 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers
  NCT07544589 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati
• A Phase 1/1b Study of IAM1363 in HER2 Cancers
  NCT06253871 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
  NCT07217171 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
  NCT04657068 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati, Maumee
• A Study of ASP1002 in Adults for Treatment of Solid Tumors
  NCT05719558 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
  NCT06750094 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Canton, Cleveland
• A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
  NCT06662786 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Canton, Cleveland, Independence, Mansfield
• A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
  NCT03526835 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland, Columbus, Maumee
• A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
  NCT06792695 · Phase: Phase 2 · Ages: 18 Years to 130 Years · Sex: All (male and female) · Ohio: Cleveland
• A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
  NCT06395519 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
  NCT03093116 · Phase: Phase 1, Phase 2 · Ages: 12 Years and older · Sex: All (male and female) · Ohio: Canton, Cincinnati, Cleveland, Columbus
• A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
  NCT05253651 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Canton
• A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
  NCT05592626 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
  NCT06820463 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati
• A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
  NCT06682793 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
  NCT06051695 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
  NCT07221357 · Phase: Phase 2, Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
  NCT06948448 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
  NCT07094204 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
  NCT06720987 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
  NCT07213609 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Canton
• A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
  NCT06562543 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.
  NCT07033026 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Toledo, Youngstown
• Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
  NCT05334069 · Phase: Not specified · Ages: 40 Years to 75 Years · Sex: All (male and female) · Ohio: Akron, Barberton, Beavercreek, Belpre
• Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
  NCT05174169 · Phase: Phase 2, Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Akron, Alliance, Avon, Barberton
• DESTINY-PANTUMOUR04
  NCT07124000 · Phase: Not specified · Ages: 18 Years to 130 Years · Sex: All (male and female) · Ohio: Canton, Maumee
• Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers
  NCT06746012 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.
  NCT06263088 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
  NCT07018869 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati
• Evaluation of Gixam's Efficacy Predicting the Presence of Advanced and Non-advanced Colorectal Neoplasia in a FIT Negative Population
  NCT07623902 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 84 Years · Sex: All (male and female) · Ohio: Mentor
• FOG-001 in Locally Advanced or Metastatic Solid Tumors
  NCT05919264 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer
  NCT07446322 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Canton
• Family Communications After Genetic Testing
  NCT07143487 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Alliance, Beavercreek, Boardman, Canton
• Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
  NCT05080673 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 70 Years · Sex: All (male and female) · Ohio: Beachwood, Beavercreek, Boardman, Centerville
• Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis
  NCT07044362 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• Integrated Cancer Repository for Cancer Research
  NCT02012699 · Phase: Not specified · Ages: 19 Years to 110 Years · Sex: All (male and female) · Ohio: Alliance, Canton
• JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
  NCT06973564 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
  NCT06026410 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
  NCT06073431 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Beavercreek, Belpre, Boardman, Cincinnati
• Lead-212 PSV359 Therapy for Patients With Solid Tumors
  NCT06710756 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 90 Years · Sex: All (male and female) · Ohio: Columbus
• MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
  NCT06586515 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati, Cleveland
• Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
  NCT03998202 · Phase: Not specified · Ages: 60 Years and older · Sex: All (male and female) · Ohio: Chillicothe, Columbus, Findlay, Mount Vernon
• Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer
  NCT06205485 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Centerville, Cincinnati, Columbus, Dayton
• ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
  NCT05059444 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati, Cleveland, Toledo
• Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
  NCT05856981 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Canton
• Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
  NCT03715933 · Phase: Phase 1 · Ages: 12 Years to 85 Years · Sex: All (male and female) · Ohio: Cincinnati, Cleveland
• Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
  NCT05786924 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
  NCT06950385 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland, Columbus
• Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
  NCT07228832 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Akron, Canton, Cincinnati, Cleveland
• Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections
  NCT07351071 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• SMP-3124LP in Adults With Advanced Solid Tumors
  NCT06526819 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
  NCT03452774 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · Ohio: Cincinnati, Columbus, Mayfield Heights
• Safety of HRX215 in Patients After Minor and Major Liver Resection
  NCT06638502 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · Ohio: Cleveland
• Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
  NCT04981119 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Columbus
• Strategies for Optimizing a Mailed FIT Program in Appalachia
  NCT07173985 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 74 Years · Sex: All (male and female) · Ohio: Columbus
• Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
  NCT07030257 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland, Maumee
• Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
  NCT05489211 · Phase: Phase 2 · Ages: 18 Years to 130 Years · Sex: All (male and female) · Ohio: Cincinnati, Columbus
• Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
  NCT03947385 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati, Cleveland
• Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
  NCT05855200 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Akron, Cincinnati, Cleveland
• Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
  NCT06445062 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati
• Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
  NCT06040541 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati
• Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
  NCT04429542 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma
  NCT05433142 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati, Columbus
• Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
  NCT05176483 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
  NCT07283939 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati
• Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
  NCT07222800 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati, Cleveland, Fairfield
• TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
  NCT04485013 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati, Columbus, Toledo
• Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
  NCT04851119 · Phase: Phase 1, Phase 2 · Ages: 12 Months to 30 Years · Sex: All (male and female) · Ohio: Cincinnati
• Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays
  NCT05234177 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Canton, Cincinnati, Columbus, Toledo
• Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
  NCT05863195 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland, Columbus, Youngstown
• Testing for Safety and Colorectal Cancer Preventive Effects of ONC201
  NCT05630794 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland, Columbus
• Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study
  NCT05673148 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Centerville, Cleveland, Columbus, Dayton
• Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer
  NCT06654037 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati, West Chester
• Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
  NCT05803382 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cincinnati, West Chester
• The Cancer of the Pancreas Screening-5 CAPS5)Study
  NCT02000089 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
  NCT04585750 · Phase: Phase 1, Phase 2 · Ages: 12 Years and older · Sex: All (male and female) · Ohio: Cleveland
• The Ohio State University (OSU) SCREEN Community Program
  NCT06666192 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · Ohio: Columbus
• The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors
  NCT04624555 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)
  NCT06641310 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland
• Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer
  NCT07407647 · Phase: Phase 2 · Ages: 50 Years and older · Sex: Female · Ohio: Columbus
• cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
  NCT05366881 · Phase: Not specified · Ages: 40 Years and older · Sex: All (male and female) · Ohio: Cleveland
• ctHPVDNA Response-Adapted Chemoradiation +/- Retifanlimab Treatment in Locally-Advanced Anal Cancer
  NCT07425054 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · Ohio: Cleveland