Clinical trials recruiting for Osteoarthritis (OA) of the Knee

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee
  NCT06884865 · Phase: Phase 2 · Ages: 45 Years to 80 Years · Sex: All (male and female) · 40 locations
• Anti-Diabetic Drug, Exercise and Healthy Diet for Knee Osteoarthritis With Overweight/Obesity
  NCT07065591 · Phase: Early Phase 1 · Ages: 40 Years to 80 Years · Sex: All (male and female) · 2 locations
• COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty
  NCT06809998 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Clinical Study of Acupuncture Treatment of Knee Osteoarthritis
  NCT06805188 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Cohort of Lower-Extremity Sports Injuries and Degeneration(Yongjiang Cohort)
  NCT07592871 · Phase: Not specified · Ages: 18 Years to 90 Years · Sex: All (male and female) · 1 location
• Effects of Different Relaxation Therapies on Pain and Sleep in Hip and Knee Arthroplasty Patients
  NCT07354542 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Efficacy of Platelet-Rich Plasma Added to Hyaluronic Acid in Knee Osteoarthritis
  NCT07785401 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Efficacy of Platelet-Rich Plasma Combined With Hyaluronic Acid in Knee Osteoarthritis
  NCT07784907 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal
  NCT07673328 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 85 Years · Sex: All (male and female) · 1 location
• Evaluation of Choose to Move Replacement Ready (CTM-RR)
  NCT07696650 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• Feasibility of Choose to Move Replacement Ready
  NCT07069179 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• GENicular Nerve Block in KNEE Arthroplasty
  NCT07589127 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Imageless Navigation Versus Image-Based Navigation in Robotic-Assisted Total Knee Arthroplasty for Knee Osteoarthritis
  NCT07522489 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Impact of Bone-Marrow Aspirate Injections in Knee Arthroscopy
  NCT06893302 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 64 Years · Sex: All (male and female) · 1 location
• Long-Term Effects of Mobithron Advance on Knee Osteoarthritis Aims to Investigate the Effects of Mobithron Advance on OA Progression
  NCT07323745 · Phase: Early Phase 1 · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• Mako Cementless TKA vs Mako Cemented TKA
  NCT06929871 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Neurolysis for the Treatment of Medial Chronic Knee Pain Due to Osteoarthritis
  NCT07178951 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Novel Extended-Release Bupivacaine Polymer for Sustained Pain Relief Following Total Knee Arthroplasty
  NCT07775248 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection
  NCT07804446 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 5 locations
• Percutaneous Neurostimulation in Knee Osteoarthritis
  NCT07637682 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Personalized Digital Training Intervention to Reduce Inflammation by Correcting Pathological Movement Patterns in Pre-stage Knee Osteoarthritis After Anterior Cruciate Ligament Reconstruction
  NCT06596824 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 50 Years · Sex: All (male and female) · 2 locations
• Pharmacist-physiotherapist Collaborative Management for Early Knee Osteoarthritis
  NCT06681142 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• Platelet Rich Plasma for Musculoskeletal Conditions
  NCT07231471 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Systemic Oral Glucocorticoids for the Treatment of Acute Osteoarthritis Pain in the Emergency Department
  NCT06603662 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• The Effectiveness of a Herbal Supplement in Osteoarthritis.
  NCT07324746 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• The Effects of Functional Electrical Stimulation (FES) and Exercise on the Quadriceps in Patients With Knee Osteoarthritis
  NCT07309003 · Phase: Not specified · Ages: 50 Years to 65 Years · Sex: All (male and female) · 2 locations
• The Efficacy of Transcutaneous Pulsed Radiofrequency Acupuncture for Knee Osteoarthritis
  NCT06702046 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 85 Years · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Osteoarthritis (OA) of the Knee often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Osteoarthritis (OA) of the Knee trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.