Clinical trials recruiting for Total Knee Arthroplasty

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• Binaural Beats for Postoperative Pain and Anxiety Reduction
  NCT07437469 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 99 Years · Sex: All (male and female) · 1 location
• Comparing Efficiency of Mirogabalin and Pregabalin in Primary TKA
  NCT06328062 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 85 Years · Sex: All (male and female) · 1 location
• Cryotherapy Versus Standard Care in Reducing Opioid Consumption After Total Knee Arthroplasty
  NCT07630337 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Effect of iPACK and BiFeS Blocks on Quality of Recovery After Total Knee Arthroplasty
  NCT07248072 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• GENicular Nerve Block in KNEE Arthroplasty
  NCT07589127 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Infiltration or Nerve Blocks in Addition to Adductor Canal Block
  NCT06920186 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Investigating Patient Satisfaction With Smart Knee Implants
  NCT06968143 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Kinematic and Mechanical Alignment Randomized Trial
  NCT06787417 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Mako Cementless TKA vs Mako Cemented TKA
  NCT06929871 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Oral vs Intravenous Dexamethasone in Total Knee Arthroplasty
  NCT07442812 · Phase: Not specified · Ages: 50 Years to 80 Years · Sex: All (male and female) · 1 location
• Prediction of Postoperative Outcomes After TKA Using Instrumented Insoles and DNN
  NCT07367789 · Phase: Not specified · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
  NCT06083480 · Phase: Phase 4 · Ages: 50 Years and older · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Total Knee Arthroplasty often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Total Knee Arthroplasty trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.