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A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer
NCT07049055 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Summit
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A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors
NCT05932862 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: New Brunswick
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A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
NCT07644559 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: East Brunswick
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A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer
NCT05365581 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: New Brunswick
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A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors
NCT07488676 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Hackensack
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A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
NCT04895709 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Hackensack
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A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma
NCT03334708 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Middletown, Montvale
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A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
NCT06778863 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Hackensack
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A Study of ELI-002 7P, With or Without Tislelizumab, in People With Pancreatic Cancer
NCT07671339 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Basking Ridge, Middletown, Montvale
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A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
NCT07277413 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: East Brunswick
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A Study of Magnetic Resonance Imaging of the Pancreas for Cancer Screening
NCT07612046 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Basking Ridge, Middletown, Montvale
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A Study of Multiparametric Ultrasound Imaging Methods
NCT07270237 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Basking Ridge, Middletown, Montvale
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A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
NCT05877599 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: New Brunswick
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A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue
NCT05837767 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Basking Ridge, Middletown, Montvale
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A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC
NCT05968326 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Basking Ridge, Middletown, Montvale
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A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
NCT07522073 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Hackensack, Morristown
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A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
NCT06179160 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Hackensack
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A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
NCT07409272 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Basking Ridge, Middletown, Montvale, Morristown
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A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
NCT07094204 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Hackensack
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A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
NCT06989437 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Morristown, New Brunswick, Somerville, Summit
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APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
NCT04858334 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Basking Ridge, Camden, Middletown, Montvale
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Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
NCT07562152 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Belleville
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CT-95 in Advanced Cancers Associated With Mesothelin Expression
NCT06756035 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Hackensack
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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT05334069 ·
Phase: Not specified ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female)
· New Jersey: Englewood, Freehold, Hackettstown, Morristown
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Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers
NCT04239573 ·
Phase: Not specified ·
Ages: 50 Years to 75 Years ·
Sex: All (male and female)
· New Jersey: East Orange, Englewood, Freehold, Morristown
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Evaluating Novel Therapies in ctDNA Positive GI Cancers
NCT05482516 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Hackensack
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Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease (EXPAND): A Randomized Phase III Trial
NCT06593431 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Camden, Voorhees Township
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Hyperpolarized C Pyruvate Magnetic Resonance Imaging, and Blood-Based Biomarkers for Early Detection of Pancreatic Adenocarcinoma in Patients With Intraductal Papillary Mucinous Neoplasms
NCT06305728 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Basking Ridge, Middletown, Montvale
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Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC
NCT03257033 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Camden, Morristown
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Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer
NCT05296421 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Livingston, New Brunswick
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KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
NCT06026410 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: New Brunswick
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Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula
NCT06807437 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Livingston, New Brunswick
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ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
NCT05059444 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: East Brunswick
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Outcomes of Ablation of Unresectable Pancreatic Cancer Using the NanoKnife Irreversible Electroporation System-
NCT06937996 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Englewood
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Pancreatic Cancer Detection Consortium
NCT06388967 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Morristown
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Pancreatic Cancer Early Detection Consortium
NCT04970056 ·
Phase: Not specified ·
Ages: 18 Years to 90 Years ·
Sex: All (male and female)
· New Jersey: Hackensack
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Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors
NCT07145255 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: East Brunswick
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RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT
NCT01885299 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· New Jersey: Egg Harbor, Red Bank, Toms River
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Relacorilant With Nab-Paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Adenocarcinoma
NCT07259317 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: East Brunswick, Morristown
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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
NCT03452774 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· New Jersey: New Brunswick
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Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors
NCT05799274 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Princeton
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Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
NCT06445062 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Morristown
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Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors
NCT04900818 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: New Brunswick
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Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )
NCT07621718 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: East Brunswick
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Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
NCT06958328 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Basking Ridge, Camden, Cherry Hill, Middletown
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Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
NCT04172532 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New Jersey: Livingston, Long Branch, New Brunswick
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VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
NCT03556228 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· New Jersey: Englewood, Florham Park, Morristown