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A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease
NCT06565195 ·
Phase: Phase 1 ·
Ages: 30 Years to 80 Years ·
Sex: All (male and female)
· Florida: Naples
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A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
NCT06680830 ·
Phase: Phase 2 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Florida: Boca Raton, Gainesville, Orlando, Tampa
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A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease
NCT04991831 ·
Phase: Not specified ·
Ages: 30 Years to 99 Years ·
Sex: All (male and female)
· Florida: Miami
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A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)
NCT06285643 ·
Phase: Phase 2 ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· Florida: Boca Raton, Gainesville, Miami, Orlando
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A Study of Buntanetap in Participants With PD
NCT07284784 ·
Phase: Phase 2, Phase 3 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· Florida: Aventura, Daytona Beach, DeLand, Ocala
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A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
NCT06765668 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Aventura, Boca Raton, Miami, Orlando
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A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
NCT06809400 ·
Phase: Phase 1 ·
Ages: 30 Years to 85 Years ·
Sex: All (male and female)
· Florida: Maitland, Naples, Orlando, Port Orange
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A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
NCT06976268 ·
Phase: Phase 2, Phase 3 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Florida: Atlantis, Boca Raton, Maitland
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A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
NCT07432958 ·
Phase: Phase 2 ·
Ages: 30 Years to 80 Years ·
Sex: All (male and female)
· Florida: Boca Raton, Hallandale, Miami, Orlando
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A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
NCT07174310 ·
Phase: Phase 3 ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female)
· Florida: Atlantis, Boca Raton, Lady Lake, Maitland
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A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy
NCT07804615 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Altamonte Springs, Aventura, Miami, Naples
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A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
NCT06944522 ·
Phase: Phase 3 ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Miami, Tampa
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A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
NCT07330258 ·
Phase: Not specified ·
Ages: 45 Years to 75 Years ·
Sex: All (male and female)
· Florida: Miami, Orlando, Tampa
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Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease
NCT07428447 ·
Phase: Not specified ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female)
· Florida: Orlando
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Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
NCT06719583 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Gainesville
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Cross-System Effects of Acute Intermittent Hypercapnia-Based Interventions in PD
NCT07674264 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female)
· Florida: Gainesville
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Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease
NCT07207122 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 80 Years ·
Sex: All (male and female)
· Florida: Gainesville
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Efficacy of a Breathwork Practice (SKY) on Well-Being of Individuals With Parkinson's Disease (iPD) and Care Partners
NCT06581523 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Coral Springs, Davie, Fort Lauderdale
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Electrophysiology-based DBS Programming for PD
NCT07348705 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years to 89 Years ·
Sex: All (male and female)
· Florida: Gainesville
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Globus Pallidus Stimulation to Treat Insomnia
NCT04116996 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Florida: Jacksonville
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Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease
NCT05266417 ·
Phase: Phase 2 ·
Ages: 30 Years and older ·
Sex: All (male and female)
· Florida: Davie, Hialeah, Miami, The Villages
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Listener Training for Improved Intelligibility of People With Parkinson's Disease
NCT06815263 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Tallahassee
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Low Versus High Load Training and Parkinson's Disease
NCT07378813 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female)
· Florida: Coral Gables
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Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease
NCT07005180 ·
Phase: Phase 2 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Florida: Gainesville
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Neurophysiology of Locomotor Adaptation and Freezing of Gait in Parkinson's Disease
NCT06911229 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Florida: Gainesville
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PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
NCT04477785 ·
Phase: Not specified ·
Ages: 30 Years and older ·
Sex: All (male and female)
· Florida: Boca Raton, Gainesville, Tampa
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Parkinson's Foundation PD GENEration Genetic Registry
NCT04994015 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Aventura, Boca Raton, Gainesville, Miami
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Parkinson's Foundation Surveys
NCT05066763 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Miami
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Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
NCT04373317 ·
Phase: Phase 4 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Florida: Gainesville
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Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States:
NCT07219927 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Boca Raton
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Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
NCT02071134 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Gainesville, Jacksonville, Miami, Tallahassee
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SAD Study in Patients With Parkinson's Disease and Motor Fluctuations
NCT07422675 ·
Phase: Phase 1 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Florida: Hallandale, Maitland
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Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
NCT05395624 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Florida: Jacksonville
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Use of CereGate Therapy for Freezing of Gait in PD
NCT05292794 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years to 80 Years ·
Sex: All (male and female)
· Florida: Miami